Publikationen

Sie erhalten auf dieser Seite einen Überblick über unsere Publikationen aus den Jahren 

2015
  • Enhanced FHL2 and TGF-ß1 Expression Is Associated With Invasive Growth and Poor Survival in Malignant Melanomas.
    Am J Clin Pathol. 2015;143(2): 248-56 (Impact(2014)=2.514, Typ=Article; Journal Article)
    Westphal P, Mauch C, Florin A, Czerwitzki J, Olligschläger N, Wodtke C, Schüle R, Büttner R, Friedrichs N
  • ET-1 Induced Downregulation of MRP2 via miRNA 133a - A Marker for Tubular Nephrotoxicity?
    Am J Nephrol. 2015;41(3): 191-9 (Impact(2014)=2.669, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Loeser H, von Brandenstein M, Herschung A, Schlosser M, Büttner R, Fries JW
  • Endogenous Il10 Alleviates the Systemic Antiviral Cellular Immune Response and T Cell-Mediated Immunopathology in Select Organs of Acutely LCMV-Infected Mice.
    Am J Pathol. 2015;185(11): 3025-38 (Impact(2014)=4.591, Typ=Article; Journal Article)
    Jakobshagen K, Ward B, Baschuk N, Huss S, Brunn A, Malecki M, Fiolka M, Rappl G, Corogeanu D, Karow U, Schiller P, Abken H, Heukamp LC, Deckert M, Krönke M, Utermöhlen O
  • Both GLUT-1 and GLUT-14 are Independent Prognostic Factors in Gastric Adenocarcinoma.
    Ann Surg Oncol. 2015;22 Suppl 3: 822-31 (Impact(2014)=3.93, Typ=Article; Journal Article)
    Berlth F, Mönig S, Pinther B, Grimminger P, Maus M, Schlösser H, Plum P, Warnecke-Eberz U, Harismendy O, Drebber U, Bollschweiler E, Hölscher A, Alakus H
  • Immunohistochemical analysis of cytochrome C oxidase facilitates differentiation between oncocytoma and chromophobe renal cell carcinoma.
    Appl Immunohistochem Mol Morphol. 2015;23(1): 54-9 (Impact(2014)=2.012, Typ=Article; Journal Article)
    Adam AC, Scriba A, Ortmann M, Huss S, Kahl P, Steiner S, Störkel S, Büttner R
  • Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy.
    BMC Cancer. 2015;15: 291 (Impact(2014)=3.362, Typ=Article; Journal Article)
    Heydt C, Kumm N, Fassunke J, Künstlinger H, Ihle MA, Scheel A, Schildhaus HU, Haller F, Büttner R, Odenthal M, Wardelmann E, Merkelbach-Bruse S
  • Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling.
    BMC Cancer. 2015;15: 638 (Impact(2014)=3.362, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Rastetter RH, Blömacher M, Drebber U, Marko M, Behrens J, Solga R, Hojeili S, Bhattacharya K, Wunderlich CM, Wunderlich FT, Odenthal M, Ziemann A, Eichinger L, Clemen CS
  • Rationale, design and objectives of ARegPKD, a European ARPKD registry study.
    BMC Nephrol. 2015;16: 22 (Impact(2014)=1.69, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Ebner K, Feldkoetter M, Ariceta G, Bergmann C, Buettner R, Doyon A, Duzova A, Goebel H, Haffner D, Hero B, Hoppe B, Illig T, Jankauskiene A, Klopp N, König J, Litwin M, Mekahli D, Ranchin B, Sander A, Testa S, Weber LT, Wicher D, Yuzbasioglu A, Zerres K, Dötsch J, Schaefer F, Liebau MC, ESCAPE Study Group , GPN Study Group , Cachat F, Seeman T, Bruechle N, Querfeld U, Kirschstein M, Benz K, Buescher R, Latta K, Pohl M, Gross O, Patzer L, Kemper M, Pape L, Bernhardt W, Wuehl E, Beck B, Benzing T, Wygoda S, Wiemann D, Klaus G, Fehrenbach H, Wallot M, Lange-Sperandio B, Uetz B, Kranz B, Boeswald M, Staude H, Leichter HE, Billing H, Beringer O, Ilmoja ML, Lara L, Sallay P, Ardissino G, Emma F, Cerkauskiene R, Drozdz D, Niemirska A, Szczepanska M, Zaniew M, Paripovi? D, Anarat A, Baskin E, Caliskan S, Candan C, Emre S, Dursun I, Ekinci Z, Delibas A, Kerecuk L, Guay-Woodford L
  • Genotype/Phenotype correlations in patients with hereditary breast cancer.
  • Breast Care OR. 2015;10(1): 22-6 (Impact(2014)=0.627, Typ=Review; Journal Article; Review)
    Wittersheim M, Büttner R, Markiefka B
  • Reprogramming of the ERRß and ERß target gene landscape triggers tamoxifen resistance in breast cancer.
    Cancer Res. 2015;75(4): 720-31 (Impact(2014)=9.329, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Thewes V, Simon R, Schroeter P, Schlotter M, Anzeneder T, Büttner R, Benes V, Sauter G, Burwinkel B, Nicholson RI, Sinn HP, Schneeweiss A, Deuschle U, Zapatka M, Heck S, Lichter P
  • A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.
    Cell. 2015;162(1): 146-59 (Impact(2014)=32.242, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Dietlein F, Kalb B, Jokic M, Noll EM, Strong A, Tharun L, Ozreti? L, Künstlinger H, Kambartel K, Randerath WJ, Jüngst C, Schmitt A, Torgovnick A, Richters A, Rauh D, Siedek F, Persigehl T, Mauch C, Bartkova J, Bradley A, Sprick MR, Trumpp A, Rad R, Saur D, Bartek J, Wolf J, Büttner R, Thomas RK, Reinhardt HC
  • A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer (vol 162, pg 146, 2015)
    Cell. 2015;162(5): 1169-1169 (Impact(2014)=32.242, Typ=Correction)
    Dietlein Felix, Kalb Bastian, Jokic Mladen, Noll ElisaM, Strong Alexander, Tharun Lars, Ozretic Luka, Kuenstlinger Helen, Kambartel Kato, Randerath WinfriedJ, Juengst Christian, Schmitt Anna, Torgovnick Alessandro, Richters Andre, Rauh Daniel, Siedek Florian, Persigehl Thorsten, Mauch Cornelia, Bartkova Jirina, Bradley Allan, Sprick MartinR, Trumpp Andreas, Rad Roland, Saur Dieter, Bartek Jiri, Wolf Juergen, Buettner Reinhard, Thomas RomanK, Reinhardt HChristian
  • Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers.
    Clin Cancer Res. 2015;21(8): 1904-15 (Impact(2014)=8.722, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Oberthuer A, Juraeva D, Hero B, Volland R, Sterz C, Schmidt R, Faldum A, Kahlert Y, Engesser A, Asgharzadeh S, Seeger R, Ohira M, Nakagawara A, Scaruffi P, Tonini GP, Janoueix-Lerosey I, Delattre O, Schleiermacher G, Vandesompele J, Speleman F, Noguera R, Piqueras M, Bénard J, Valent A, Avigad S, Yaniv I, Grundy RG, Ortmann M, Shao C, Schwab M, Eils R, Simon T, Theissen J, Berthold F, Westermann F, Brors B, Fischer M
  • MET amplification status in therapy-naïve adeno- and squamous cell carcinomas of the lung.
    Clin Cancer Res. 2015;21(4): 907-15 (Impact(2014)=8.722, Typ=Article; Journal Article)
    Schildhaus HU, Schultheis AM, Rüschoff J, Binot E, Merkelbach-Bruse S, Fassunke J, Schulte W, Ko YD, Schlesinger A, Bos M, Gardizi M, Engel-Riedel W, Brockmann M, Serke M, Gerigk U, Hekmat K, Frank KF, Reiser M, Schulz H, Krüger S, Stoelben E, Zander T, Wolf J, Buettner R
  • Immunomodulation by splenectomy or by FTY720 protects the heart against ischemia reperfusion injury.
    Clin Exp Pharmacol Physiol. 2015;42(11): 1168-77 (Impact(2014)=2.372, Typ=Article; Journal Article)
    Goltz D, Huss S, Ramadori E, Büttner R, Diehl L, Meyer R
  • White-Light or Narrow-Band Imaging Colonoscopy in Surveillance of Ulcerative Colitis: A Prospective Multicenter Study.
    Clin Gastroenterol Hepatol. 2015;13(10): 1776-1781.e1 (Impact(2014)=7.896, Typ=Journal Article; Research Support, Non-U.S. Gov't)
    Leifeld L, Rogler G, Stallmach A, Schmidt C, Zuber-Jerger I, Hartmann F, Plauth M, Drabik A, Hofstädter F, Dienes HP, Kruis W, Detect Dysplasia Study Group , Büttner R, Löser H, Drebber U, Dignass A, Terjung B, Sauerbruch T, Schreiber S, Lanyi B, Pfuetzer R, Morgenstern J, Böhm S, Böcker U, Rupf AK, Appenroth B, Biecker E, Walldorf J
  • Complete Remission of Metastatic Neuroendocrine Paragastric Carcinoma After "Neoadjuvant" Peptide Receptor Radionuclide Therapy and Surgery.
    Clin Nucl Med. 2015;40(8): 667-9 (Impact(2014)=3.931, Typ=Journal Article)
    Schmidt MC, Uhrhan K, Fischer T, Schmitz S, Markiefka B, Drzezga A, Stippel D
  • Vimentin 3, the new hope, differentiating RCC versus oncocytoma.
    Dis Markers. 2015;2015: 368534 (Impact(2014)=1.562, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    von Brandenstein M, Puetz K, Schlosser M, Löser H, Kallinowski JP, Gödde D, Buettner R, Störkel S, Fries JW
  • Expression of podoplanin and prognosis in oropharyngeal cancer.
    Eur Arch Otorhinolaryngol. 2015;272(7): 1749-54 (Impact(2014)=1.545, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Preuss SF, Anagiotos A, Seuthe IM, Drebber U, Wedemeyer I, Kreppel M, Semrau R, Eslick GD, Klussmann JP, Huebbers CU
  • Clinical and genetic presentation of high-level cMET-amplified Non-small cell lung cancer (NSCLC) with adenocarcinoma histology
    Eur J Cancer. 2015;51 3: S646-S646 (Impact(2014)=5.417, Typ=Meeting Abstract)
    Eisert A, Scheffler M, Frank R, Gogl L, Scheel A, Merkelbach-Bruse S, Michels S, Fischer R, Buttner R, Wolf J
  • KEAP1-mutations and NFE2L2-mutations in patients with non-small cell lung cancer (NSCLC)
    Eur J Cancer. 2015;51 3: S645-S645 (Impact(2014)=5.417, Typ=Meeting Abstract)
    Frank R, Scheffler M, Michels S, Eisert A, Fischer R, Koenig K, Merkelbach-Bruse S, Serke M, Ko YD, Gerigk U, Geist T, Heukamp L, Buettner R, Wolf J
  • Clinical and molecular characteristics of non-small cell lung cancer in patients harboring CTNNB1 mutations
    Eur J Cancer. 2015;51 3: S647-S647 (Impact(2014)=5.417, Typ=Meeting Abstract)
    Gogl L, Scheffler M, Ihle M, Michels SYF, Fischer R, Serke MH, Gerigk U, Woempner C, Krueger S, Kaminsky B, Schulte W, Hoeffken G, Merkelbach-Bruse S, Buettner R, Wolf J
  • Broad implementation of next generation sequencing based lung cancer genotyping in clinical routine within a nationwide health care provider network in Germany
    Eur J Cancer. 2015;51 3: S597-S597 (Impact(2014)=5.417, Typ=Meeting Abstract)
    Kostenko A, Kron F, Scheffler M, Michels S, Sueptitz J, Fischer R, Merkelbach-Bruse S, Scheel A, De-Mary P, Glossmann JP, Buettner R, Wolf J
  • PD-L1 expression in small cell neuroendocrine carcinomas.
    Eur J Cancer. 2015;51(3): 421-6 (Impact(2014)=5.417, Typ=Journal Article; Journal Article)
    Schultheis AM, Scheel AH, Ozreti? L, George J, Thomas RK, Hagemann T, Zander T, Wolf J, Buettner R
  • Contribution of mast cell-derived VEGF to tumor growth
    Exp Dermatol. 2015;24(3): E33-E33 (Impact(2014)=3.762, Typ=Meeting Abstract)
    Rabenhorst A, Leja S, Florin A, Heukamp LC, Ullrich RT, Foerster A, Roers A, Buettner R, Hartmann K
  • Implementing amplicon-based next generation sequencing in the diagnosis of small cell lung carcinoma metastases.
    Exp Mol Pathol. 2015;99(3): 682-6 (Impact(2014)=2.706, Typ=Article; Journal Article)
    Meder L, König K, Fassunke J, Ozreti? L, Wolf J, Merkelbach-Bruse S, Heukamp LC, Buettner R
  • The wish to cure and the curiosity to investigate - or how I used my life to become a physician-scientist.
    Frontiers in medicine. 2015;2: 9 (Impact: liegt nicht vor, Typ=Journal Article; Review)
    Fries JW
  • Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data.
    Genome Biol. 2015;16: 7 (Impact(2014)=10.81, Typ=Journal Article; Journal Article; Research Support, Non-U.S. Gov't)
    Fernandez-Cuesta L, Sun R, Menon R, George J, Lorenz S, Meza-Zepeda LA, Peifer M, Plenker D, Heuckmann JM, Leenders F, Zander T, Dahmen I, Koker M, Schöttle J, Ullrich RT, Altmüller J, Becker C, Nürnberg P, Seidel H, Böhm D, Göke F, Ansén S, Russell PA, Wright GM, Wainer Z, Solomon B, Petersen I, Clement JH, Sänger J, Brustugun OT, Helland Å, Solberg S, Lund-Iversen M, Buettner R, Wolf J, Brambilla E, Vingron M, Perner S, Haas SA, Thomas RK
  • [Surgical therapy for pulmonary metastases from malignant melanoma].
    Hautarzt. 2015;66(1): 65-73 (Impact(2014)=0.564, Typ=English Abstract; Journal Article; Journal Article; English Abstract)
    Macherey S, Schlaak M, Doerr F, Grönke S, Heldwein M, Quaas A, Zander T, Hekmat K
  • Prognostic quality of the Union Internationale Contre le Cancer/American Joint Committee on Cancer TNM classification, 7th edition, for cancer of the maxillary sinus
  • Head Neck. 2015;37(3): 400-6 (Impact(2014)=2.641, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Kreppel M, Amir Manawi NN, Scheer M, Nickenig HJ, Rothamel D, Dreiseidler T, Drebber U, Zinser M, Zöller JE, Guntinas-Lichius O, Preuss SF
  • Circulating microRNAs as a marker for liver injury in human immunodeficiency virus patients.
    Hepatology. 2015;61(1): 46-55 (Impact(2014)=11.055, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Anadol E, Schierwagen R, Elfimova N, Tack K, Schwarze-Zander C, Eischeid H, Noetel A, Boesecke C, Jansen C, Dold L, Wasmuth JC, Strassburg CP, Spengler U, Rockstroh JK, Odenthal M, Trebicka J
  • Molecular markers predicting lymph node metastasis in early esophageal cancer.
    Histol Histopathol. 2015;30(10): 1193-202 (Impact(2014)=2.096, Typ=Article; Journal Article)
    Plum PS, Warnecke-Eberz U, Dhaouadi O, Alakus H, Drebber U, Metzger R, Prenzel KL, Hölscher AH, Bollschweiler E
  • INDICATORS OF RITUXIMAB RESPONSIVENESS IN ANTIBODY-MEDIATED REJECTION AFTER KIDNEY TRANSPLANTATION
    Hum Immunol. 2015;76 1: 65-65 (Impact(2014)=2.138, Typ=Meeting Abstract)
    Immenschuh S, Zilian E, Daemmrich ME, Gwinner W, Becker JU, Blume CA
  • HEME OXYGENASE-1 MODULATES HLA CLASS I ANTIBODY-DEPENDENT ENDOTHELIAL CELL ACTIVATION.
    Hum Immunol. 2015;76 1: 15-15 (Impact(2014)=2.138, Typ=Meeting Abstract)
    Zilian E, Saragih H, Hiller O, Aljabri A, Figueiredo C, Blasczyk R, Theilmeier G, Becker JU, Larmann J, Immenschuh S
  • Serum microRNA profiles as prognostic/predictive markers in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction.
    Int J Cancer. 2015;137(1): 230-7 (Impact(2014)=5.085, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Odenthal M, Hee J, Gockel I, Sisic L, Schmitz J, Stoecklein NH, Driemel C, Möhlendick B, Schmidt T, Knoefel WT, Lang H, Büttner R, Ott K, Vallböhmer D
  • SRC inhibition represents a potential therapeutic strategy in liposarcoma.
    Int J Cancer. 2015;137(11): 2578-88 (Impact(2014)=5.085, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Sievers E, Trautmann M, Kindler D, Huss S, Gruenewald I, Dirksen U, Renner M, Mechtersheimer G, Pedeutour F, Åman P, Nishio J, Schildhaus HU, Kirfel J, Schirmacher P, Wardelmann E, Buettner R, Hartmann W
  • Utility of different massive parallel sequencing platforms for mutation profiling in clinical samples and identification of pitfalls using FFPE tissue.
    Int J Mol Med. 2015;36(5): 1233-43 (Impact(2014)=2.088, Typ=Article; Journal Article)
    Fassunke J, Haller F, Hebele S, Moskalev EA, Penzel R, Pfarr N, Merkelbach-Bruse S, Endris V
  • Differential diagnosis of solitary fibrous tumors: A study of 454 soft tissue tumors indicating the diagnostic value of nuclear STAT6 relocation and ALDH1 expression combined with in situ proximity ligation assay.
    Int J Oncol. 2015;46(6): 2595-605 (Impact(2014)=3.025, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Ouladan S, Trautmann M, Orouji E, Hartmann W, Huss S, Büttner R, Wardelmann E
  • Circulating ADAM17 Level Reflects Disease Activity in Proteinase-3 ANCA-Associated Vasculitis.
    J Am Soc Nephrol. 2015;26(11): 2860-70 (Impact(2014)=9.343, Typ=Journal Article)
    Bertram A, Lovric S, Engel A, Beese M, Wyss K, Hertel B, Park JK, Becker JU, Kegel J, Haller H, Haubitz M, Kirsch T
  • Invasive Squamous Cell Carcinoma in a Sternotomy Incision.
    J Card Surg. 2015;30(11): 820-1 (Impact(2014)=0.89, Typ=Editorial Material; Journal Article)
    Wacker M, Fries JW, Rahmanian P, Wahlers T
  • Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma.
    J Clin Endocrinol Metab. 2015;100(1): E119-28 (Impact(2014)=6.209, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Elbelt U, Trovato A, Kloth M, Gentz E, Finke R, Spranger J, Galas D, Weber S, Wolf C, König K, Arlt W, Büttner R, May P, Allolio B, Schneider JG
  • GLUT-1 and GLUT-14 as independent prognostic factors in gastric adenocarcinoma.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Berlth Felix, Grimminger PeterPhili, Maus MartinKarl, Pinther Berit, Plum Patrick, Schloesser HansAnton, Drebber Uta, Bollschweiler Elfriede, Hoelscher ArnulfHein, Moenig StefanPaul, Alakus Hakan
  • Genetic variability and clinical presentation of patients with non-small cell lung cancer (NSCLC) harboring MET-amplifications.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Eisert Anna, Scheffler Matthias, Michels SebastianY, Schultheis AnneMaria, Frank Rieke, Koenig Katharina, Merkelbach-Bruse Sabine, Fischer Rieke, Serke MonikaHeid, Ko Yon-Dschun, Gerigk Ulrich, Geist Thomas, Heukamp LukasCarl, Buettner Reinhard, Wolf Juergen
  • KEAP1-mutations in patients with non-small cell lung cancer (NSCLC).
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Frank Rieke, Scheffler Matthias, Michels SebastianY, Eisert Anna, Fischer Rieke, Koenig Katharina, Merkelbach-Bruse Sabine, Serke MonikaHeid, Ko Yon-Dschun, Gerigk Ulrich, Geist Thomas, Heukamp LukasCarl, Buettner Reinhard, Wolf Juergen
  • Clinical and molecular characteristics of non-small cell lung cancer in patients harboring CTNNB1 mutations.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Gogl Leonie, Scheffler Matthias, Michaela Ihle, Michels SebastianY, Fischer Rieke, Serke MonikaHeid, Gerigk Ulrich, Wompner Claudia, Krueger Stefan, Kaminsky Britta, Schulte Wolfgang, Hoeffken Gert, Merkelbach-Bruse Sabine, Buettner Reinhard, Wolf Juergen
  • The network genomic medicine cost reimbursement model for implementation of comprehensive lung cancer genotyping in clinical routine.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Kostenko Anna, Glossmann JanPeter, Michels SebastianY, Sueptitz Juliane, Scheffler Matthias, Fischer Rieke, Markiefka Birgid, Scheel Andreas, De Mary Peter, Kron Florian, Buettner Reinhard, Wolf Juergen, Network Genomic Medicine Lung Canc
  • SORAVE: A phase I trial to evaluate safety and efficacy of combination therapy with everolimus and sorafenib.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Mattonet C, Nogova L, Scheffler M, Michels SYF, Kahraman D, Kobe C, Fuhr U, Suleiman AA, Tian YY, Soergel F, Toepelt K, Schnell R, Schlaak M, Rhiem K, Buettner R, Wolf J
  • ROS1 rearrangement in non-small cell lung cancer (NSCLC): Prognostic and predicitve impact and genetic variability.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Scheffler Matthias, Schultheis AnneMaria, Teixido Cristina, Michels SebastianY, Morales-Espinosa Daniela, Viteri Santiago, Merkelbach-Bruse Sabine, Fischer Rieke, Fassunke Jana, Sebastian Martin, Serke MonikaHeid, Randerath Winfried, Gerigk Ulrich, Ko Yon-Dschun, Krueger Stefan, Schnell Roland, Rothe Achim, Rosell Rafael, Buettner Reinhard, Wolf Juergen, NGM ROS1 Grp
  • Comprehensive characterization of PDL-1 and CTLA-4 in gastric cancer.
    J Clin Oncol. 2015;33 S(15): - (Impact(2014)=18.443, Typ=Meeting Abstract)
    Schloesser HansAnton, Drebber Uta, Thelen Martin, Kloth Michael, Rothschild Sasha, Garcia-Marquez Maria, Zoghi Sharam, Urbanski Alexander, Alakus Hakan, Schauss Astrid, Theurich Sebastian, Warnecke-Eberz Ute, Stippel DirkLudger, Hoelscher ArnulfHein, Zander Thomas, Moenig StefanPaul, von Bergwelt-Baildon MichaelS
  • Comprehensive lymph node morphometry in rectal cancer using acetone compression.
    J Clin Pathol. 2015;68(6): 458-64 (Impact(2014)=2.915, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Scheel AH, Reineke RA, Sprenger T, Lokka S, Kitz J, Ghadimi BM, Rüschoff J, Liersch T, Middel P
  • Expression of ezrin in oral squamous cell carcinoma: Prognostic impact and clinicopathological correlations.
    J Craniomaxillofac Surg. 2015;43(9): 1899-905 (Impact(2014)=2.933, Typ=Article; Journal Article)
    Safi AF, Nickenig HJ, Rothamel D, Zirk M, Thiele O, Grandoch A, Scheer M, Zinser M, Zöller J, Drebber U, Kreppel M
  • Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.
    J Exp Med. 2015;212(12): 2057-75 (Impact(2014)=12.515, Typ=Journal Article)
    Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A
  • EVOLUTION ANALYSIS BY DEEP SEQUENCING REVEALED HIGH IMPACT OF THE MITOCHONDRIAL GENOME IN HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
    J Hepatol. 2015;62 2: S416-S416 (Impact(2014)=11.336, Typ=Meeting Abstract)
    Amer W, Quass A, Drebber U, Eischeid H, Koitzsch U, Arens A, Vollbrecht C, Buettner R, Odenthal M
  • ULTRA-DEEP SEQUENCING OF MULTIPLEX-PCR ENRICHED HOTSPOT AND DISEASE-RELATED TARGETS IN HEPATOCELLULAR CARCINOMA
    J Hepatol. 2015;62 2: S428-S428 (Impact(2014)=11.336, Typ=Meeting Abstract)
    Amer W, Koitzsch U, Vollbrecht C, Quaas A, Samara R, Arens A, Buettner R, Drebber U, Huang J, Odenthal M
  • DINSTICT INTRAHEPATIC CYTOKINE PROFILES FOR THE DIFFERENTIATON OF ACUTE CELLULAR REJECTION VS RECURRENT HEPATITIS C IN LIVER TRANSPLANTED PATIENTS
    J Hepatol. 2015;62 2: S311-S312 (Impact(2014)=11.336, Typ=Meeting Abstract)
    Fytili P, Krech T, Gonnermann A, Grosshennig A, Jonigk D, Lehner F, Manns MP, Koch A, Becker JU, Wedemeyer H
  • IMPACT OF ORGAN AND NON-ORGAN-SPECIFIC AUTOANTIBODIES ON THE TREATMENT OUTCOME OF PATIENTS WITH HEPATITIS D VIRUS INFECTIONJ Hepatol. 2015;62 2: S531-S532 (Impact(2014)=11.336, Typ=Meeting Abstract)
    Zachou K, Yurdaydin C, Drebber U, Schlaphoff V, Dienes HP, Manns MP, Wedemeyer H, Dalekos N, HIDIT-1 Study Grp
  • Mast cell-derived vascular endothelial growth factor contributes to tumor growth
    J Invest Dermatol. 2015;135 2: S19-S19 (Impact(2014)=7.216, Typ=Meeting Abstract)
    Rabenhorst A, Leja S, Florin A, Foerster A, Heukamp LC, Ullrich RT, Willenborg S, Eming S, Buettner R, Hartmann K
  • Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients.
    J Thorac Oncol. 2015;10(7): 1049-57 (Impact(2014)=5.282, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    König K, Peifer M, Fassunke J, Ihle MA, Künstlinger H, Heydt C, Stamm K, Ueckeroth F, Vollbrecht C, Bos M, Gardizi M, Scheffler M, Nogova L, Leenders F, Albus K, Meder L, Becker K, Florin A, Rommerscheidt-Fuss U, Altmüller J, Kloth M, Nürnberg P, Henkel T, Bikár SE, Sos ML, Geese WJ, Strauss L, Ko YD, Gerigk U, Odenthal M, Zander T, Wolf J, Merkelbach-Bruse S, Buettner R, Heukamp LC
  • Spatial Tumor Heterogeneity in Lung Cancer with Acquired Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance: Targeting High-Level MET-Amplification and EGFR T790M Mutation Occurring at Different Sites in the Same Patient.
    J Thorac Oncol. 2015;10(6): e40-3 (Impact(2014)=5.282, Typ=Article; Journal Article)
    Scheffler M, Merkelbach-Bruse S, Bos M, Fassunke J, Gardizi M, Michels S, Groneck L, Schultheis AM, Malchers F, Leenders F, Kobe C, König K, Heukamp LC, Sos ML, Thomas RK, Büttner R, Wolf J
  • Micro RNAs miR-106a, miR-122 and mir-197 are increased in severe acute viral hepatitis with coagulopathy
    J Viral Hepat. 2015;22 2: 43-44 (Impact(2014)=3.909, Typ=Meeting Abstract)
    Weseslindtner L, Schulte I, Eischeid H, Strassl R, Hofer H, Popow-Kraupp T, Odenthal M, Holzmann H
  • Impact of the MRN Complex on Adeno-Associated Virus Integration and Replication during Coinfection with Herpes Simplex Virus 1.
    J Virol. 2015;89(13): 6824-34 (Impact(2014)=4.439, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Millet R, Jolinon N, Nguyen XN, Berger G, Cimarelli A, Greco A, Bertrand P, Odenthal M, Büning H, Salvetti A
  • Early identification of renal transplant recipients with high risk of polyomavirus-associated nephropathy.
    Med Microbiol Immunol (Berl). 2015;204(6): 657-64 (Impact(2014)=3.038, Typ=Article; Journal Article)
    Teutsch K, Schweitzer F, Knops E, Kaiser R, Pfister H, Verheyen J, Göbel H, Cingöz T, Di Cristanziano V
  • Impact of updated HER2 testing guidelines in breast cancer-re-evaluation of HERA trial fluorescence in situ hybridization data.
    Mod Pathol. 2015;28(12): 1528-34 (Impact(2014)=6.187, Typ=Article; Journal Article)
    Stoss OC, Scheel A, Nagelmeier I, Schildhaus HU, Henkel T, Viale G, Jasani B, Untch M, Rüschoff J
  • miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours.
    Mol Oncol. 2015;9(7): 1421-33 (Impact(2014)=5.331, Typ=Article; Journal Article)
    Ihle MA, Trautmann M, Kuenstlinger H, Huss S, Heydt C, Fassunke J, Wardelmann E, Bauer S, Schildhaus HU, Buettner R, Merkelbach-Bruse S
  • Our 2015 approach to invasive pulmonary aspergillosis.
    Mycoses. 2015;58(6): 375-82 (Impact(2014)=2.239, Typ=Review; Journal Article; Research Support, Non-U.S. Gov't)
    Liss B, Vehreschild JJ, Bangard C, Maintz D, Frank K, Grönke S, Michels G, Hamprecht A, Wisplinghoff H, Markiefka B, Hekmat K, Vehreschild MJ, Cornely OA
  • Comprehensive genomic profiles of small cell lung cancer.
    Nature. 2015;524(7563): 47-53 (Impact(2014)=41.456, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural)
    George J, Lim JS, Jang SJ, Cun Y, Ozreti? L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK
  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
    Nature. 2015;526(7575): 700-4 (Impact(2014)=41.456, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, Menon R, Krämer A, Roncaioli JL, Sand F, Heuckmann JM, Ikram F, Schmidt R, Ackermann S, Engesser A, Kahlert Y, Vogel W, Altmüller J, Nürnberg P, Thierry-Mieg J, Thierry-Mieg D, Mariappan A, Heynck S, Mariotti E, Henrich KO, Gloeckner C, Bosco G, Leuschner I, Schweiger MR, Savelyeva L, Watkins SC, Shao C, Bell E, Höfer T, Achter V, Lang U, Theissen J, Volland R, Saadati M, Eggert A, de Wilde B, Berthold F, Peng Z, Zhao C, Shi L, Ortmann M, Büttner R, Perner S, Hero B, Schramm A, Schulte JH, Herrmann C, O'Sullivan RJ, Westermann F, Thomas RK, Fischer M
  • UPREGULATION OF MIR-21-5P AND MIR-708-5P IN CELLULAR CRESCENTS OF IGA GLOMERULONEPHRITIS
    Nephrol Dial Transplant. 2015;30 3: - (Impact(2014)=3.577, Typ=Meeting Abstract)
    Becker JanU, Bockmeyer ClemensL
  • DETECTION OF GLOMERULAR CD80 (B7-1) MRNA BY QRT-PCR AND ON PODOCYTES BY IMMUNOSTAINS ON PARAFFIN EMBEDDED BIOPSIES WITH FSGS
    Nephrol Dial Transplant. 2015;30 3: - (Impact(2014)=3.577, Typ=Meeting Abstract)
    Becker JanU, Bockmeyer ClemensL
  • A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.
    Oncogene. 2015;34(26): 3357-68 (Impact(2014)=8.459, Typ=Journal Article; Research Support, Non-U.S. Gov't)
    Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprüssel A, Lindner S, De Preter K, Florin A, Heukamp LC, Klein-Hitpass L, Astrahantseff K, Kumps C, Speleman F, Eggert A, Westermann F, Schramm A, Schulte JH
  • Serum microRNA profiles as prognostic or predictive markers in the multimodality treatment of patients with gastric cancer.
    Oncol Lett. 2015;10(2): 869-874 (Impact(2014)=1.554, Typ=Article; Journal Article)
    Sisic L, Vallböhmer D, Stoecklein NH, Blank S, Schmidt T, Driemel C, Möhlendick B, Knoefel WT, Odenthal M, Ott K
  • Combined Chk1-and MK2-inhibition displays robust synergy in KRAS-mutant cancer
    Oncol Res Treat. 2015;38 5: 169-169 (Impact(2014)=0, Typ=Meeting Abstract)
    Dietlein F, Kalb B, Jokic M, Torgovnick A, Schmitt A, Buettner R, Thomas R, Reinhardt HC
  • Clinical and genetic presentation of high-level cMET-amplified Non-small cell lung cancer (NSCLC) with adenocarcinoma histology
    Oncol Res Treat. 2015;38 5: 16-16 (Impact(2014)=0, Typ=Meeting Abstract)
    Eisert A, Scheffier M, Gogl L, Frank R, Scheel A, Merkelbach-Bruse S, Michels S, Fischer R, Buttner R, Wolf J
  • Tumor-infiltrating B lymphocytes characterized by CD79a and MUM1 independently predict outcome in patients with non-small cell lung cancer
    Oncol Res Treat. 2015;38 5: 13-13 (Impact(2014)=0, Typ=Meeting Abstract)
    Fischer RN, Scheel AH, Rothschild SI, Schlosser HA, Wolf J, Buttner R, Ansen S, von Bergwelt-Baildon M
  • KEAP1-mutations and NFE2L2-mutations in patients with non-small cell lung cancer (NSCLC)
    Oncol Res Treat. 2015;38 5: 268-268 (Impact(2014)=0, Typ=Meeting Abstract)
    Frank R, Scheffler M, Michels S, Eisert A, Gogl L, Fischer R, Konig K, Merkelbach-Bruse S, Serke M, Ko YD, Gerigk U, Geist T, Heukamp L, Buttner R, Wolf J
  • Mutation Profiling of Lung Cancers with Long-Term Response to Gefitinib Therapy.
    Oncol Res Treat. 2015;38(11): 560-9 (Impact(2014)=0, Typ=Article; Journal Article)
    Gautschi O, Stadelmann C, Aebersold-Keller F, König K, Büttner R, Heukamp LC, Betticher D, Baumann C, Buser K, Calderoni A, Casty A, D'Addario G, Irlé C, Mamot C, Morant R, Trojan A, Pellicioli E, Jehle-Schwertfeger S, Aebi S, Diebold J
  • Clinical and molecular characteristics of non-small cell lung cancer in patients harboring CTNNB1 mutations
    Oncol Res Treat. 2015;38 5: 269-269 (Impact(2014)=0, Typ=Meeting Abstract)
    Gogl L, Scheffier M, Ihle M, Michels S, Fischer R, Serke M, Gerigk U, Wompner C, Kruger S, Kaminsky B, Schulte W, Hoffken G, Merkelbach-Bruse S, Buttner R, Wolf J, Lung Canc Grp Cologne
  • Induction therapy with intercalated TKI and chemotherapy in NSCLC with activating EGFR mutation in stages II-IIIB: Neolntercal
    Oncol Res Treat. 2015;38 5: 140-140 (Impact(2014)=0, Typ=Meeting Abstract)
    Griesinger F, Sebastian M, Serke M, Buettner R, Waller C, Reinmuth N, Graeven U, Lueers A, Radke S, Karatas A, Heukamp L, Tiemann M, Overbeck T
  • Comprehensive multiplex genotyping in lung cancer: challenges and opportunities of interdisciplinary networking using the example of the Network Genomic Medicine
    Oncol Res Treat. 2015;38 5: 268-268 (Impact(2014)=0, Typ=Meeting Abstract)
    Kostenko A, Kron F, Scheffler M, Michels S, Sueptitz J, Fischer R, Merkelbach-Bruse S, Scheel A, De-Mary P, Glossmann JP, Buettner R, Wolf J, Netzwerk Genomische Med
  • The histone code reader SPIN1 controls RET signaling in liposarcoma.
    Oncotarget. 2015;6(7): 4773-89 (Impact(2014)=6.359, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Franz H, Greschik H, Willmann D, Ozreti? L, Jilg CA, Wardelmann E, Jung M, Buettner R, Schüle R
  • Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity.
    Oncotarget. 2015;6(20): 18224-37 (Impact(2014)=6.359, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Grünewald I, Vollbrecht C, Meinrath J, Meyer MF, Heukamp LC, Drebber U, Quaas A, Beutner D, Hüttenbrink KB, Wardelmann E, Hartmann W, Büttner R, Odenthal M, Stenner M
  • c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia.
    Oncotarget. 2015;6(2): 825-35 (Impact(2014)=6.359, Typ=Article; Journal Article)
    Kübler K, Heinenberg S, Rudlowski C, Keyver-Paik MD, Abramian A, Merkelbach-Bruse S, Büttner R, Kuhn W, Schildhaus HU
  • FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro.
    Oncotarget. 2015;6(24): 20215-30 (Impact(2014)=6.359, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Künstlinger H, Fassunke J, Schildhaus HU, Brors B, Heydt C, Ihle MA, Mechtersheimer G, Wardelmann E, Büttner R, Merkelbach-Bruse S
  • ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability.
    Oncotarget. 2015;6(12): 10577-85 (Impact(2014)=6.359, Typ=Article; Journal Article)
    Scheffler M, Schultheis A, Teixido C, Michels S, Morales-Espinosa D, Viteri S, Hartmann W, Merkelbach-Bruse S, Fischer R, Schildhaus HU, Fassunke J, Sebastian M, Serke M, Kaminsky B, Randerath W, Gerigk U, Ko YD, Krüger S, Schnell R, Rothe A, Kropf-Sanchen C, Heukamp L, Rosell R, Büttner R, Wolf J
  • PIK3CA mutations in non-small cell lung cancer (NSCLC): genetic heterogeneity, prognostic impact and incidence of prior malignancies.
    Oncotarget. 2015;6(2): 1315-26 (Impact(2014)=6.359, Typ=Article; Journal Article)
    Scheffler M, Bos M, Gardizi M, König K, Michels S, Fassunke J, Heydt C, Künstlinger H, Ihle M, Ueckeroth F, Albus K, Serke M, Gerigk U, Schulte W, Töpelt K, Nogova L, Zander T, Engel-Riedel W, Stoelben E, Ko YD, Randerath W, Kaminsky B, Panse J, Becker C, Hellmich M, Merkelbach-Bruse S, Heukamp LC, Büttner R, Wolf J
  • Intermittent high-dose treatment with erlotinib enhances therapeutic efficacy in EGFR-mutant lung cancer
    Oncotarget. 2015;6(36): 38458-38468 (Impact(2014)=6.359, Typ=Congresses)
    Schoettle Jakob, Chatterjee Sampurna, Volz Caroline, Siobal Maike, Florin Alexandra, Rokitta Dennis, Hinze Yvonne, Dietlein Felix, Plenker Dennis, Koenig Katharina, Albus Kerstin, Heuckmann JohannesM, Rauh Daniel, Franz Thomas, Neumaier Bernd, Fuhr Uwe, Heukamp LukasC, Ullrich RolandT
  • Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type?
    Oncotarget. 2015;6(27): 23905-16 (Impact(2014)=6.359, Typ=Journal Article)
    Vassella E, Langsch S, Dettmer MS, Schlup C, Neuenschwander M, Frattini M, Gugger M, Schäfer SC
  • [Prolapse of the upper lacrimal punctum].
    Ophthalmologe. 2015;112(9): 788-90 (Impact(2014)=0.504, Typ=Editorial Material; Journal Article)
    Bucher F, Fries JW, Hos D, Koch KR, Cursiefen C, Heindl LM
  • Impact of coupling techniques of an active middle ear device to the round window membrane for the backward stimulation of the cochlea.
    Otol Neurotol. 2015;36(1): 111-7 (Impact(2014)=1.787, Typ=Journal Article)
    Gostian AO, Pazen D, Ortmann M, Luers JC, Anagiotos A, Hüttenbrink KB, Beutner D
  • Circulating miRNA-122 levels are associated with hepatic necroinflammation and portal hypertension in HIV/HCV coinfection.
    PLoS ONE. 2015;10(2): e0116768 (Impact(2014)=3.234, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Jansen C, Reiberger T, Huang J, Eischeid H, Schierwagen R, Mandorfer M, Anadol E, Schwabl P, Schwarze-Zander C, Warnecke-Eberz U, Strassburg CP, Rockstroh JK, Peck-Radosavljevic M, Odenthal M, Trebicka J
  • MET gene copy number alterations and expression of MET and hepatocyte growth factor are potential biomarkers in angiosarcomas and undifferentiated pleomorphic sarcomas.
    PLoS ONE. 2015;10(4): e0120079 (Impact(2014)=3.234, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Schmitz K, Koeppen H, Binot E, Fassunke J, Künstlinger H, Ihle MA, Heydt C, Wardelmann E, Büttner R, Merkelbach-Bruse S, Rüschoff J, Schildhaus HU
  • Criteria Used in Clinical Practice to Guide Immunosuppressive Treatment in Patients with Primary Sclerosing Cholangitis.
    PLoS ONE. 2015;10(10): e0140525 (Impact(2014)=3.234, Typ=Article; Journal Article)
    Schulze K, Weismüller TJ, Bubenheim M, Huebener P, Zenouzi R, Lenzen H, Rupp C, Gotthardt D, de Leuw P, Teufel A, Zimmer V, Reiter FP, Rust C, Tharun L, Quaas A, Weidemann SA, Lammert F, Sarrazin C, Manns MP, Lohse AW, Schramm C, German PSC Study Group
  • Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing.
    PLoS ONE. 2015;10(6): e0129544 (Impact(2014)=3.234, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Vollbrecht C, Mairinger FD, Koitzsch U, Peifer M, Koenig K, Heukamp LC, Crispatzu G, Wilden L, Kreuzer KA, Hallek M, Odenthal M, Herling CD, Buettner R
  • Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation.
    PLoS ONE. 2015;10(12): e0145306 (Impact(2014)=3.234, Typ=Article; Journal Article)
    Zilian E, Saragih H, Vijayan V, Hiller O, Figueiredo C, Aljabri A, Blasczyk R, Theilmeier G, Becker JU, Larmann J, Immenschuh S
  • Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer.
    Pathol Res Pract. 2015;211(2): 171-4 (Impact(2014)=1.397, Typ=Journal Article; Journal Article)
    Al-Nomani L, Friedrichs J, Schüle R, Büttner R, Friedrichs N
  • [Chances and risks of blood-based molecular pathological analysis of circulating tumor cells (CTC) and cell-free DNA (cfDNA) in personalized cancer therapy: positional paper from the study group on liquid biopsy of the working group for molecular patholog
    Pathologe. 2015;36(1): 92-7 (Impact(2014)=0.406, Typ=Editorial Material; Journal Article; Review)
    Dahl E, Jung A, Fassunke J, Hummel M, Penzel R, Dietmaier W, Laßmann S
  • TELOMERASE ACTIVATION BY RECURRENT GENOMIC REARRANGEMENTS IN HIGH-RISK NEUROBLASTOMA
    Pediatr Blood Cancer. 2015;62 4: S149-S150 (Impact(2014)=2.386, Typ=Meeting Abstract)
    Peifer M, Roels F, Hertwig F, Menon R, Kraemer A, Buettner R, Perner S, Schramm A, Schulte JH, Hero B, O'Sullivan RJ, Westermann F, Thomas RK, Fischer M
  • AREGPKD - A EUROPEAN ARPKD REGISTRY STUDY
    Pediatr Nephrol. 2015;30(9): 1673-1674 (Impact(2014)=2.856, Typ=Meeting Abstract)
    Ebner K, Feldkoetter M, Ariceta G, Bergmann C, Buettner R, Doyon A, Duzova A, Goebel H, Haffner D, Hero B, Hoppe B, Illig T, Jankauskiene A, Klopp N, Konig J, Litwin M, Mekahli D, Ranchin B, Sander A, Testa S, Weber LT, Wicher D, Yuzbasioglu A, Zerres K, Dotsch J, Schaefer F, Liebau MC
  • Retroperitoneal schwannomas of renal and pararenal origin: presentation of two case reports.
    Rare Tumors. 2015;7(1): 5616 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Herden J, Drebber U, Ural Y, Zimmer S, Wille S, Engelmann UH
  • Exosomal onco-miRs from serum of patients with adenocarcinoma of the esophagus: comparison of miRNA profiles of exosomes and matching tumor.
    Tumour Biol. 2015;36(6): 4643-53 (Impact(2014)=3.611, Typ=Article; Journal Article)
    Warnecke-Eberz U, Chon SH, Hölscher AH, Drebber U, Bollschweiler E
  • TGF-ß1-dependent induction and nuclear translocation of FHL2 promotes keratin expression in pilomatricoma.
    Virchows Arch. 2015;466(2): 199-208 (Impact(2014)=2.651, Typ=Journal Article; Journal Article)
    Friedrichs J, Fink D, Mauch C, Kindler D, Hartmann W, Schüle R, Buettner R, Friedrichs N
  • [S2k Guideline non-alcoholic fatty liver disease].
    Z Gastroenterol. 2015;53(7): 668-723 (Impact(2014)=1.052, Typ=Article; Journal Article)
    Roeb E, Steffen HM, Bantel H, Baumann U, Canbay A, Demir M, Drebber U, Geier A, Hampe J, Hellerbrand C, Pathil-Warth A, Schattenberg JM, Schramm C, Seitz HK, Stefan N, Tacke F, Tannapfel A, Lynen Jansen P, Bojunga J
  • [Colorectal Carcinoma with Suspected Lynch Syndrome: A Multidisciplinary Algorithm].
    Zentralbl Chir. 2015;140(6): 591-9 (Impact(2014)=1.048, Typ=Article; Journal Article; English Abstract)
    Schneider R, Schneider C, Büttner R, Reinacher-Schick A, Tannapfel A, Fürst
2014
  • Incubation and nanostructure formation on n- and p-type Si(100) and Si(111) at various doping levels induced by sub-nanojoule femto- and picosecond near-infrared laser pulses
  • APPL SURF SCI. 2014;314: 21-29 (Impact: liegt nicht vor, Typ=Article)
    Schule M, Afshar M, Feili D, Seidel H, Konig K, Straub M
  • Masked polycythemia vera diagnosed according to WHO and BCSH classification.
    Am J Hematol. 2014;89(2): 199-202 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Barbui T, Thiele J, Carobbio A, Gisslinger H, Finazzi G, Rumi E, Luigia Randi M, Vannucchi AM, Gisslinger B, Müllauer L, Ruggeri M, Rambaldi A, Tefferi A
  • Masked polycythemia vera (mPV): results of an international study.
    Am J Hematol. 2014;89(1): 52-4 (Impact: liegt nicht vor, Typ=Article; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't)
    Barbui T, Thiele J, Gisslinger H, Finazzi G, Carobbio A, Rumi E, Luigia Randi M, Betozzi I, Vannucchi AM, Pieri L, Carrai V, Gisslinger B, Müllauer L, Ruggeri M, Rambaldi A, Tefferi A
  • Discriminating between essential thrombocythemia and masked polycythemia vera in JAK2 mutated patients.
    Am J Hematol. 2014;89(6): 588-90 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Barbui T, Thiele J, Carobbio A, Guglielmelli P, Rambaldi A, Vannucchi AM, Tefferi A
  • Circulating hematopoietic progenitor cells in essential thrombocythemia versus prefibrotic/early primary myelofibrosis.
    Am J Hematol. 2014;89(12): 1157-8 (Impact: liegt nicht vor, Typ=Letter; Letter)
    Geissler K, Jäger E, Gisslinger B, Thiele J, Schwarzinger I, Gisslinger H
  • Prognostic classification of histopathologic response to neoadjuvant therapy in esophageal adenocarcinoma.
    Ann Surg. 2014;260(5): 779-85 (Impact: liegt nicht vor, Typ=Article; Proceedings Paper; Journal Article)
    Hölscher AH, Drebber U, Schmidt H, Bollschweiler E
  • Homozygous GNAS 393C-allele carriers with locally advanced esophageal cancer fail to benefit from platinum-based preoperative chemoradiotherapy.
    Ann Surg Oncol. 2014;21(13): 4375-82 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Alakus H, Bollschweiler E, Hölscher AH, Warnecke-Eberz U, Frazer KA, Harismendy O, Lowy AM, Mönig SP, Eberz PM, Maus M, Drebber U, Siffert W, Metzger R
  • Validation of 2-mm tissue microarray technology in gastric cancer. Agreement of 2-mm TMAs and full sections for Glut-1 and Hif-1 alpha.
    Anticancer Res. 2014;34(7): 3313-20 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Berlth F, Mönig SP, Schlösser HA, Maus M, Baltin CT, Urbanski A, Drebber U, Bollschweiler E, Hölscher AH, Alakus H
  • Clinical significance of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) for metastatic sentinel lymph node involvement in breast cancer.
    Anticancer Res. 2014;34(8): 4457-62 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Harms W, Malter W, Krämer S, Drebber U, Drzezga A, Schmidt M
  • The "COLD-PCR approach" for early and cost-effective detection of tyrosine kinase inhibitor resistance mutations in EGFR-positive non-small cell lung cancer.
    Appl Immunohistochem Mol Morphol. 2014;22(2): 114-8 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Mairinger FD, Vollbrecht C, Streubel A, Roth A, Landt O, Walter HF, Kollmeier J, Mairinger T
  • Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations.
    BMC Cancer. 2014;14: 13 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Ihle MA, Fassunke J, König K, Grünewald I, Schlaak M, Kreuzberg N, Tietze L, Schildhaus HU, Büttner R, Merkelbach-Bruse S
  • CGARS: cancer genome analysis by rank sums.
    Bioinformatics. 2014;30(9): 1295-6 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Lu X, Thomas RK, Thomas RK, Peifer M
  • Dynamic of bone marrow fibrosis regression predicts survival after allogeneic stem cell transplantation for myelofibrosis.
    Biol Blood Marrow Transplant. 2014;20(6): 812-5 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Kröger N, Zabelina T, Alchalby H, Stübig T, Wolschke C, Ayuk F, von Hünerbein N, Kvasnicka HM, Thiele J, Kreipe HH, Büsche G
  • Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis.
    Blood. 2014;124(16): 2507-13; quiz 2615 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Tefferi A, Guglielmelli P, Larson DR, Finke C, Wassie EA, Pieri L, Gangat N, Fjerza R, Belachew AA, Lasho TL, Ketterling RP, Hanson CA, Rambaldi A, Finazzi G, Thiele J, Barbui T, Pardanani A, Vannucchi AM
  • A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC.
    Cancer Discov. 2014;4(5): 592-605 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural)
    Dietlein F, Thelen L, Jokic M, Jachimowicz RD, Ivan L, Knittel G, Leeser U, van Oers J, Edelmann W, Heukamp LC, Reinhardt HC
  • CD74-NRG1 Fusions in Lung Adenocarcinoma.
    Cancer Discov. 2014;4(4): 415-22 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Fernandez-Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, Ortiz-Cuaran S, Peifer M, Bos M, Daßler J, Malchers F, Schöttle J, Vogel W, Dahmen I, Koker M, Ullrich RT, Wright GM, Russell PA, Wainer Z, Solomon B, Brambilla E, Nagy-Mignotte H, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Altmüller J, Becker C, Nürnberg P, Heuckmann JM, Stoelben E, Petersen I, Clement JH, Sänger J, Muscarella LA, la Torre A, Fazio VM, Lahortiga I, Perera T, Ogata S, Parade M, Brehmer D, Vingron M, Heukamp LC, Buettner R, Zander T, Wolf J, Perner S, Ansén S, Haas SA, Yatabe Y, Thomas RK
  • Cell-Autonomous and Non-Cell-Autonomous Mechanisms of Transformation by Amplified FGFR1 in Lung Cancer.
    Cancer Discov. 2014;4(2): 246-57 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Malchers F, Dietlein F, Schöttle J, Lu X, Nogova L, Albus K, Fernandez-Cuesta L, Heuckmann JM, Gautschi O, Diebold J, Plenker D, Gardizi M, Scheffler M, Bos M, Seidel D, Leenders F, Richters A, Peifer M, Florin A, Mainkar PS, Karre N, Chandrasekhar S, George J, Silling S, Rauh D, Zander T, Ullrich R, Reinhardt HC, Ringeisen F, Buttner R, Heukamp LC, Wolf J, Thomas RK
  • Transient antiangiogenic treatment improves delivery of cytotoxic compounds and therapeutic outcome in lung cancer.
    Cancer Res. 2014;74(10): 2816-24 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Chatterjee S, Wieczorek C, Schöttle J, Siobal M, Hinze Y, Franz T, Florin A, Adamczak J, Heukamp LC, Neumaier B, Ullrich RT
  • Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3.
    Carcinogenesis. 2014;35(2): 315-23 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Comparative Study)
    Yang R, Chen B, Pfütze K, Buch S, Steinke V, Holinski-Feder E, Stöcker S, von Schönfels W, Becker T, Schackert HK, Royer-Pokora B, Kloor M, Schmiegel WH, Büttner R, Engel C, Lascorz Puertolas J, Försti A, Kunkel N, Bugert P, Schreiber S, Krawczak M, Schafmayer C, Propping P, Hampe J, Hemminki K, Burwinkel B
  • Sensitizing protective tumor microenvironments to antibody-mediated therapy.
    Cell. 2014;156(3): 590-602 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural)
    Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT
  • Case of myocardial relapse of a T-cell lymphoma after hematopoietic stem cell transplantation demonstrated by cardiovascular magnetic resonance and endomyocardial biopsy.
    Circulation. 2014;130(6): e44-7 (Impact: liegt nicht vor, Typ=Editorial Material; Journal Article; Case Reports)
    Baeßler B, Rudolph V, Friedrichs N, Maintz D, Bunck AC
  • Tuberous-sclerosis complex-related cell signaling in the pathogenesis of lung cancer.
    Diagn Pathol. 2014;9: 48 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Fuchs A, König K, Heukamp LC, Fassunke J, Kirfel J, Huss S, Becker AJ, Büttner R, Majores M
  • [Chronic pulmonary Aspergillosis. Four exemplary clinical cases and literature overview].
    Dtsch Med Wochenschr. 2014;139(44): 2242-7 (Impact: liegt nicht vor, Typ=Article; Journal Article; Review; Case Reports; English Abstract)
    Schweer KE, Wittersheim M, Bangard C, Frank KF, Cornely OA
  • [A very rare cause of haemoptysis - coexistence of primary oncocytic adenoma of trachea with bronchial carcinoma].
    Dtsch Med Wochenschr. 2014;139(24): 1295-8 (Impact: liegt nicht vor, Typ=Article; Journal Article; Case Reports; English Abstract)
    Vogel Y, Wolff I, Zienkiewicz T, Büttner R, Schulte W
  • The impact of laryngeal dysplasia on the development of laryngeal squamous cell carcinoma.
    Eur Arch Otorhinolaryngol. 2014;271(3): 539-45 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Luers JC, Sircar K, Drebber U, Beutner D
  • Rapid remineralization of multiple disseminated bone lesions after high-dose cytarabine in a patient with isolated myeloid sarcoma.
    Eur J Haematol. 2014;92(6): 537-40 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Brähler S, Thielen I, Schwabe H, Engels M, Kreuzer KA, Wolf J, Ansén S
  • Decanucleotide insertion polymorphism of F7 significantly influences the risk of thrombosis in patients with essential thrombocythemia.
    Eur J Haematol. 2014;93(2): 103-11 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Buxhofer-Ausch V, Olcaydu D, Gisslinger B, Schalling M, Frantal S, Thiele J, Müllauer L, Kvasnicka HM, Watzke H, Kralovics R, Gisslinger H
  • Tumor infiltrating B-cells in primary cutaneous T-cell lymphoma correlate with disease progression and might represent a novel target for immunotherapy
    Exp Dermatol. 2014;23(3): E25-E25 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Theurich S, Schlaak M, Steguweit H, Heukamp LC, Wennhold K, Kurschat P, Rabenhorst A, Hartmann K, Shimabukuro-Vornhagen A, Schlosser H, Holtick U, Hallek M, Stadler R, von Bergwelt-Baildon M
  • Mdm2 protein expression is strongly associated with survival in malignant pleural mesothelioma.
    Future Oncol. 2014;10(6): 995-1005 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Mairinger FD, Walter RF, Ting S, Vollbrecht C, Kollmeier J, Griff S, Hager T, Mairinger T, Christoph DC, Theegarten D, Kurt Werner S, Wohlschlaeger J
  • Changing histopathological diagnostics by genome-based tumor classification.
    Genes (Basel). 2014;5(2): 444-59 (Impact: liegt nicht vor, Typ=Review; Journal Article)
    Kloth M, Buettner R
  • [Surgical therapy of lung metastases from head and neck cancer].
    HNO. 2014;62(12): 893-901; quiz 902-3 (Impact: liegt nicht vor, Typ=Article; Journal Article; English Abstract)
    Macherey S, Preuss SF, Doerr F, Grönke S, Heldwein M, Quaas A, Zander T, Hekmat K
  • CHANGES IN BONE MARROW MORPHOLOGY IN PATIENTS WITH MYELOFIBROSIS TREATED FOR UP TO 5 YEARS WITH EITHER RUXOLITINIB OR BEST AVAILABLE THERAPY
    Haematologica. 2014;99 1: 127-128 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Kvasnicka HM, Thiele J, Bueso-Ramos CE, Sun W, Cortes J, Kantarjian HM, Verstovsek S
  • [The skin's own antibiotics. Important features of antimicrobial peptides for clinical practice].
    Hautarzt. 2014;65(1): 50-5 (Impact: liegt nicht vor, Typ=Article; Journal Article; English Abstract)
    Cordes J, Wittersheim M, Harder J, Gläser R
  • Rhabdoid morphology in gastrointestinal stromal tumours (GISTs) is associated with PDGFRA mutations but does not imply aggressive behaviour.
    Histopathology. 2014;64(3): 421-30 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Schaefer IM, Ströbel P, Cameron S, Beham A, Otto C, Schildhaus HU, Agaimy A
  • Mutation of POC1B in a severe syndromic retinal ciliopathy.
    Hum Mutat. 2014;35(10): 1153-62 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural)
    Beck BB, Phillips JB, Bartram MP, Wegner J, Thoenes M, Pannes A, Sampson J, Heller R, Göbel H, Koerber F, Neugebauer A, Hedergott A, Nürnberg G, Nürnberg P, Thiele H, Altmüller J, Toliat MR, Staubach S, Boycott KM, Valente EM, Janecke AR, Eisenberger T, Bergmann C, Tebbe L, Wang Y, Wu Y, Fry AM, Westerfield M, Wolfrum U, Bolz HJ
  • High-resolution melting analysis is a sensitive diagnostic tool to detect imatinib-resistant and imatinib-sensitive PDGFRA exon 18 mutations in gastrointestinal stromal tumors.
    Hum Pathol. 2014;45(3): 573-82 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Künstlinger H, Binot E, Merkelbach-Bruse S, Huss S, Wardelmann E, Buettner R, Schildhaus HU
  • The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma.
    Int J Cancer. 2014;134(12): 2829-40 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Rothe A, Jachimowicz RD, Borchmann S, Madlener M, Keßler J, Reiners KS, Sauer M, Hansen HP, Ullrich RT, Chatterjee S, Borchmann P, Yazaki P, Koslowsky TC, Engert A, Heukamp LC, Hallek M, von Strandmann EP
  • Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: a comprehensive analysis of 3,671 families.
    Int J Cancer. 2014;135(1): 69-77 (Impact: liegt nicht vor, Typ=Article; Journal Article; Evaluation Studies; Research Support, Non-U.S. Gov't)
    Steinke V, Holzapfel S, Loeffler M, Holinski-Feder E, Morak M, Schackert HK, Görgens H, Pox C, Royer-Pokora B, von Knebel-Doeberitz M, Büttner R, Propping P, Engel C, German HNPCC Consortium , Epplen T, Kötting J, Munding J, Pox C, Schmiegel W, Schulmann K, Stemmler S, Tannapfel A, Sengteller M, Clade S, Fries N, Betz B, Goecke T, Rahner N, Möslein G, Kiehl O, Koch S, Tschischka A, Geissler M, Sieghardt A, Schröck E, Aust DE, Pistorius S, Berth H, Bläker H, Evers C, Kadmon M, Keller M, Kloor M, Moog U, Tariverdian M, Meilhaus S, Vogelsang H, Langer R, Friedrichs N, Kahl P, Enders U, Herold M, Wieland K, Zachariae S
  • MicroRNA function in the profibrogenic interplay upon chronic liver disease.
    Int J Mol Sci. 2014;15(6): 9360-71 (Impact: liegt nicht vor, Typ=Review; Journal Article; Research Support, Non-U.S. Gov't)
    Huang J, Yu X, Fries JW, Zhang L, Odenthal M
  • Activation of angiogenesis differs strongly between pulmonary carcinoids and neuroendocrine carinomas and is crucial for carcinoid tumourgenesis.
    J Cancer. 2014;5(6): 465-71 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Mairinger FD, Walter RF, Werner R, Christoph DC, Ting S, Vollbrecht C, Zarogoulidis K, Huang H, Li Q, Schmid KW, Wohlschlaeger J, Zarogoulidis P
  • Gene Expression Analysis of the 26S Proteasome Subunit PSMB4 Reveals Significant Upregulation, Different Expression and Association with Proliferation in Human Pulmonary Neuroendocrine Tumours.
    J Cancer. 2014;5(8): 646-54 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Mairinger FD, Walter RF, Theegarten D, Hager T, Vollbrecht C, Christoph DC, Worm K, Ting S, Werner R, Stamatis G, Mairinger T, Baba H, Zarogoulidis K, Huang H, Li Q, Tsakiridis K, Zarogoulidis P, Kurt Werner S, Wohlschlaeger J
  • Acquired epidermodysplasia verruciformis in an HIV-infected patient.
    J Dtsch Dermatol Ges. 2014;12(4): 353-5 (Impact: liegt nicht vor, Typ=Letter; Letter)
    Broekaert SM, Ehrchen J, Büttner R, Pfister HJ, Metze D
  • Influence of Podoplanin Expression in Cutaneous Squamous Cell Carcinoma of the Head- Neck- Regions of the Lymphogenic Metastasis and the Prognosis
    J Dtsch Dermatol Ges. 2014;12 3: 9-9 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Scheer M, Drebber U, Krakowezki A, Mauch C, Zoller JE, Kreppel M
  • Longitudinal analysis of distribution and function of plasmacytoid dendritic cells in peripheral blood and gut mucosa of HIV infected patients.
    J Infect Dis. 2014;209(6): 940-9 (Impact: liegt nicht vor, Typ=Article; Journal Article
    Lehmann C, Jung N, Förster K, Koch N, Leifeld L, Fischer J, Mauss S, Drebber U, Steffen HM, Romerio F, Fätkenheuer G, Hartmann P
  • Intraductal pressure during sialendoscopy.
    J Laryngol Otol. 2014;128(10): 897-901 (Impact: liegt nicht vor, Typ=Article; Journal Article
    Luers JC, Ortmann M, Beutner D, Hüttenbrink KB
  • LUNG ADENOCARCINOMA WITH RET FUSION: EARLY EXPERIENCE WITH DIAGNOSIS AND TARGETED THERAPY
    J Thorac Oncol. 2014;9 1(4): S38-S38 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Gautschi O, Pall G, Schultheis A, Keller FA, Gardizi M, Heuckmann J, Merkelbach-Bruse S, Diebold J, Wolf J, Heukamp L
  • Multicenter Immunohistochemical ALK-Testing of Non-Small-Cell Lung Cancer Shows High Concordance after Harmonization of Techniques and Interpretation Criteria.
    J Thorac Oncol. 2014;9(11): 1685-92 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    von Laffert M, Warth A, Penzel R, Schirmacher P, Kerr KM, Elmberger G, Schildhaus HU, Büttner R, Lopez-Rios F, Reu S, Kirchner T, Pauwels P, Specht K, Drecoll E, Höfler H, Aust D, Baretton G, Bubendorf L, Stallmann S, Fisseler-Eckhoff A, Soltermann A, Tischler V, Moch H, Penault-Llorca F, Hager H, Schäper F, Lenze D, Hummel M, Dietel M
  • Criteria for Therapy Response and Progression in Patients with Myelofibrosis Based on Bone Marrow Features. The International European LeukemiaNet Consensus Project
    Lab Invest. 2014;94 1: 357A-357A (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Kvasnicka HM, Thiele J, Bueso-Ramos CE, Hasserjian RP, Gianelli U, Van der Walt J, Molina TJ, Orazi A
  • High Concordance in Grading Reticulin Fibrosis and Hematopoietic Cellularity in Patients with Myeloproliferative Neoplasms Enrolled on Fedratinib (A JAK2 Inhibitor) Trials
    Lab Invest. 2014;94 1: 371A-372A (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Pozdnyakova O, Wu K, Patki A, Rodig SJ, Thiele J, Hasserjian R
  • Validation of Break Apart FISH Probes for the Detection of COL1A1-PDGFB Rearrangements in Dermatofibrosarcoma Protuberans
    Lab Invest. 2014;94 1: 28A-28A (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Schildhaus HU, Binot E, Buttner R, Tancheva-Poor I, Wardelmann E
  • Essential thrombocythemia with high hemoglobin levels according to the revised WHO classification.
    Leukemia. 2014;28(10): 2092-4 (Impact: liegt nicht vor, Typ=Letter; Letter; Research Support, Non-U.S. Gov't)
    Barbui T, Thiele J, Kvasnicka HM, Carobbio A, Vannucchi AM, Tefferi A
  • Rethinking the diagnostic criteria of polycythemia vera.
    Leukemia. 2014;28(6): 1191-5 (Impact: liegt nicht vor, Typ=Review; Journal Article; Review; Research Support, Non-U.S. Gov't)
    Barbui T, Thiele J, Vannucchi AM, Tefferi A
  • An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms.
    Leukemia. 2014;28(7): 1407-13 (Impact: liegt nicht vor, Typ=Review; Journal Article; Review)
    Tefferi A, Thiele J, Vannucchi AM, Barbui T
  • 25 years of endothelin research: the next generation.
    Life Sci. 2014;118(2): 77-86 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Emoto N, Vignon-Zellweger N, Lopes RA, Cacioppo J, Desbiens L, Kamato D, Leurgans T, Moorhouse R, Straube J, Wurm R, Heiden S, Ergul A, Yanagisawa M, Barton M
  • Role of immunohistochemistry for hepatitis D and hepatitis B virus in hepatitis delta.
    Liver Int. 2014;34(8): 1207-15 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Kabaçam G, Wedemeyer H, Sava? B, Keskin O, Dalekos G, Tabak F, Idilman R, Erhardt A, Yalç?n K, Bozdayi MA, Bozkaya H, Manns M, Dienes H, Yurdayd?n C, HIDIT-1 Study Group , Berg T, Böcher W, Bohle H, Buggisch P, Cornberg M, Ersöz G, Feyerabend S, Hinrichsen H, Manok M, Häussinger D, Herzog W, Hofmann WP, Plein K, Hardt H, Porst H, Mederacke I, Rigopoulou EI, Sentürk H, v Wagner E
  • Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing.
    Lung Cancer. 2014;84(3): 215-21 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Moskalev EA, Frohnauer J, Merkelbach-Bruse S, Schildhaus HU, Dimmler A, Schubert T, Boltze C, König H, Fuchs F, Sirbu H, Rieker RJ, Agaimy A, Hartmann A, Haller F
  • Criteria for Therapy Response and Progression in Patients with Myelofibrosis Based on Bone Marrow Features. The International European LeukemiaNet Consensus Project
    Mod Pathol. 2014;27 2: 357A-357A (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Kvasnicka HM, Thiele J, Bueso-Ramos CE, Hasserjian RP, Gianelli U, Van der Walt J, Molina TJ, Orazi A
  • Different micro-RNA expression profiles distinguish subtypes of neuroendocrine tumors of the lung: results of a profiling study.
    Mod Pathol. 2014;27(12): 1632-40 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Mairinger FD, Ting S, Werner R, Walter RF, Hager T, Vollbrecht C, Christoph D, Worm K, Mairinger T, Sheu-Grabellus SY, Theegarten D, Kurt Werner S, Wohlschlaeger J
  • High Concordance in Grading Reticulin Fibrosis and Hematopoietic Cellularity in Patients with Myeloproliferative Neoplasms Enrolled on Fedratinib (A JAK2 Inhibitor) Trials
    Mod Pathol. 2014;27 2: 371A-372A (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Pozdnyakova O, Wu K, Patki A, Rodig SJ, Thiele J, Hasserjian R
  • High concordance in grading reticulin fibrosis and cellularity in patients with myeloproliferative neoplasms.
    Mod Pathol. 2014;27(11): 1447-54 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Pozdnyakova O, Wu K, Patki A, Rodig SJ, Thiele J, Hasserjian RP
  • Validation of Break Apart FISH Probes for the Detection of COL1A1-PDGFB Rearrangements in Dermatofibrosarcoma Protuberans
    Mod Pathol. 2014;27 2: 28A-28A (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Schildhaus HU, Binot E, Buttner R, Tancheva-Poor I, Wardelmann E
  • Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer.
    Mod Pathol. 2014;27(2): 214-21 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Schultheis AM, Bos M, Schmitz K, Wilsberg L, Binot E, Wolf J, Büttner R, Schildhaus HU
  • Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1.
    Mol Cancer. 2014;13: 11 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Hinrichsen I, Ernst BP, Nuber F, Passmann S, Schäfer D, Steinke V, Friedrichs N, Plotz G, Zeuzem S, Brieger A
  • Our 2014 approach to mucormycosis.
    Mycoses. 2014;57(9): 519-24 (Impact: liegt nicht vor, Typ=Review; Journal Article)
    Tacke D, Koehler P, Markiefka B, Cornely OA
  • LSD1 promotes oxidative metabolism of white adipose tissue.
    Nat Commun. 2014;5: 4093 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Duteil D, Metzger E, Willmann D, Karagianni P, Friedrichs N, Greschik H, Günther T, Buettner R, Talianidis I, Metzger D, Schüle R
  • Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids.
    Nat Commun. 2014;5: 3518 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural)
    Fernandez-Cuesta L, Peifer M, Lu X, Sun R, Ozreti? L, Seidel D, Zander T, Leenders F, George J, Müller C, Dahmen I, Pinther B, Bosco G, Konrad K, Altmüller J, Nürnberg P, Achter V, Lang U, Schneider PM, Bogus M, Soltermann A, Brustugun OT, Helland Å, Solberg S, Lund-Iversen M, Ansén S, Stoelben E, Wright GM, Russell P, Wainer Z, Solomon B, Field JK, Hyde R, Davies MP, Heukamp LC, Petersen I, Perner S, Lovly CM, Cappuzzo F, Travis WD, Wolf J, Vingron M, Brambilla E, Haas SA, Buettner R, Thomas RK
  • Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer
    Nat Med. 2014;20(9): 1027-1034 (Impact: liegt nicht vor, Typ=Article)
    Loyly ChristineM, McDonald NerinaT, Chen Heidi, Ortiz-Cuaran Sandra, Heukamp LukasC, Yan Yingjun, Florin Alexandra, Ozretic Luka, Lim Diana, Wang Lu, Chen Zhao, Chen Xi, Lu Pengcheng, Paik PaulK, Shen Ronglai, Jin Hailing, Buettner Reinhard, Ansen Sascha, Perner Sven, Brockmann Michael, Bos Marc, Wolf Juergen, Gardizi Masyar, Wright GavinM, Solomon Benjamin, Russell PrudenceA, Rogers Toni-Maree, Suehara Yoshiyuki, Red-Brewer Monica, Tieu Rudy, de Stanchina Elisa, Wang Qingguo, Zhao Zhongming, Johnson DavidH, Horn Leora, Wong Kwok-Kin, Thomas RomanK, Ladanyi Marc, Pao William
  • Isothermal multiple displacement amplification: a methodical approach enhancing molecular routine diagnostics of microcarcinomas and small biopsies.
    Onco Targets Ther. 2014;7: 1441-7 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Mairinger FD, Walter RF, Vollbrecht C, Hager T, Worm K, Ting S, Wohlschläger J, Zarogoulidis P, Zarogoulidis K, Schmid KW
  • SS18-SSX fusion protein-induced Wnt/?-catenin signaling is a therapeutic target in synovial sarcoma.
    Oncogene. 2014;33(42): 5006-16 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Trautmann M, Sievers E, Aretz S, Kindler D, Michels S, Friedrichs N, Renner M, Kirfel J, Steiner S, Huss S, Koch A, Penzel R, Larsson O, Kawai A, Tanaka S, Sonobe H, Waha A, Schirmacher P, Mechtersheimer G, Wardelmann E, Büttner R, Hartmann W
  • PD-L1 expression and genotype in Non-Small Cell Lung Cancer (NSCLC)
    Oncol Res Treat. 2014;37 5: 5-6 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Ansen S, Schultheis A, Hellmich M, Leenders F, Zander T, Michels S, Brockmann M, Stoelben E, Groen H, Timens W, Buettner R, Thomas RK, Perner S, Wolf J
  • A retrospective analysis of overall survival of ALK translocation - and of EGFR mutation positive NSCLC patients treated with and without personalized therapy
    Oncol Res Treat. 2014;37 1: 91-91 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Bos M, Gardizi M, Heukamp LC, Schildhaus HU, Merkelbach-Bruse S, Nogova L, Scheffler M, Serke M, Schulz H, Kruger S, Brummendorf TH, Panse J, Schmitz S, Gerigk U, Randerath WJ, Ko YD, Kambartel K, Hunerliturkoglu AN, Buttner R, Wolf J
  • The Network Genomic Medicine: A prospective comprehensive molecular screening network for implementation of personalized lung cancer therapy
    Oncol Res Treat. 2014;37 1: 91-91 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Bos M, Gardizi M, Heukamp LC, Merkelbach-Bruse S, Schildhaus HU, Scheffler M, Nogova L, Mattonet C, Serke M, Randerath WJ, Gerigk U, Brummendorf TH, Kruger S, Panse J, Kaminski B, Reiser M, Buttner R, Wolf J
  • Genetic variability and clinical presentation of patients with non-small cell lung cancer (NSCLC) harboring MET-amplifications
    Oncol Res Treat. 2014;37 5: 8-8 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Eisert A, Scheffler M, Michels S, Schultheis A, Konig K, Merkelbach-Bruse S, Serke M, Ko YD, Gerigk U, Heukamp LC, Buttner R, Wolf J
  • Occurrence and characteristics of KEAP1-mutations in patients with non-small cell lung cancer (NSCLC)
    Oncol Res Treat. 2014;37 5: 8-8 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Frank R, Scheffler M, Michels S, Konig K, Merkelbach-Bruse S, Serke M, Ko YD, Gerigk U, Geist T, Heukamp L, Buttner R, Wolf J
  • Circulating hematopoietic progenitor cells in essential thrombocythemia versus early/prefibrotic primary myelofibrosis
    Oncol Res Treat. 2014;37 5: 59-60 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Geissler K, Jager E, Gisslinger B, Thiele J, Schwarzinger I, Gisslinger H
  • High throughput parallel amplicon sequencing of common driver mutations from FFPE lung cancer samples in molecular pathological routine diagnostics for a regional health care provider network
    Oncol Res Treat. 2014;37 1: 31-32 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Konig K, Peifer M, Bos M, Nogova L, Merkelbach-Bruse S, Stamm K, Henkel T, Thomas R, Wolf J, Buttner R, Heukamp L
  • Intraoperativeassessment of macroscopic instantaneous sections to prevent re-resection in IORT patients
    Oncol Res Treat. 2014;37 1: 16-16 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Malter W, Kapteina S, Thangarajah F, Markiefka B, Bongartz R, Semrau R, Hellmich M, Kramer S, Mallmann P
  • Single center experiences with intraoperative radiotherapy as a boost during oncoplastic breast-conserving surgery
    Oncol Res Treat. 2014;37 1: 15-16 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Malter W, Kirn V, Bongartz R, Semrau R, Markiefka B, Mallmann P, Kramer S
  • EUCROSS: A phase II trial to evaluate efficacy and safety of crizotinib treatment in advanced adenocarcinoma of the lung harbouring ROS1 translocations
    Oncol Res Treat. 2014;37 5: 65-65 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Michels S, Gardizi M, Schultheis A, Scheffler M, Karachaliou N, Teixido C, Heukamp L, Merkelbach-Bruse S, Thurat M, Nogova L, Bos M, Mattonet C, Grohe C, Sebastian M, Thomas M, Reck M, Stahel R, Pirker R, Zochbauer-Muller S, Groen H, Dingemanns AM, Smit E, Thomas R, Buttner R, Massuti B, Rosell R, Wolf J, Lungcanc Grp Cologne , Spanish Lung Canc Grp
  • RET rearrangement in adenocarcinoma of the lung
    Oncol Res Treat. 2014;37 5: 6-6 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Michels S, Schultheis A, Scheffler M, Rosner T, Merkelbach-Bruse S, Heukamp L, Engel-Riedel W, Serke M, Kruger S, Benedikter J, Gerigk U, Schulte W, Draube A, Ko YD, Buttner R, Wolf J, Lung Canc Grp Cologne
  • TRY: A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small-cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation.
    Oncol Res Treat. 2014;37 1: 92-92 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Nogova L, Gardizi M, Bos M, Scheffler M, Papachristou I, Wompner C, Heukamp L, Schildhaus HU, Fuhr U, Sos M, Eberhardt W, Wiesweg M, Schmid KW, Schuler M, Thomas R, Buttner R, Wolf J
  • SORAVE: Sorafenib and everolimus for patients with solid tumors and with KRAS mutated NSCLC - results of a phase I study
    Oncol Res Treat. 2014;37 1: 32-32 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Nogova L, Mattonet C, Gardizi M, Scheffler M, Bos M, Wompner C, Topelt K, Heukamp L, Suleiman A, Frechen S, Sorgel F, Fuhr U, Schnell R, Katay I, Behringer D, Geist T, Kaminski B, Eichstaedt M, Tummes D, Buttner R, Wolf J
  • ROS1 rearrangement in non-small cell lung cancer (NSCLC): Prognostic and predicitve impact and genetic variability
    Oncol Res Treat. 2014;37 5: 66-66 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Scheffler M, Schultheis A, Michels S, Teixido C, Hartmann W, Merkelbach-Bruse S, Sebastian M, Serke M, Kropf-Sanchen C, Wittersheim M, Puetz K, Binot E, Schildhaus HU, Heukamp LC, Rosell R, Buttner R, Wolf J
  • MIMEB: A phase II trial to evaluate FDG-PET/FLT-PET and DCE-MRI for early prediction of efficacy in patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab
    Oncol Res Treat. 2014;37 1: 92-92 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Scheffler M, Bos M, Sos M, Nogova L, Gardizi M, Mattonet C, Papachristou I, Kahraman D, Kobe C, Lammertsma A, Boellaard R, Persigehl T, Heukamp L, Buttner R, Elter T, Topelt K, Engel-Riedel W, Stoelben E, Neumaier B, Dietlein M, Zander T, Wolf J
  • Clinical and Molecular Characteristics of Non-Small Cell Lung Cancer Patients Harboring PIK3CA Mutations
    Oncol Res Treat. 2014;37 1: 92-92 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Scheffler M, Gardizi M, Bos M, Heukamp L, Konig K, Serke M, Nogova L, Topelt K, Stoelben E, Engel-Riedel W, Randerath W, Kaminsky B, Panse J, Zander T, Buttner R, Wolf J
  • Genetic heterogeneity and lack of prognostic impact of patients with non-small cell lung cancer (NSCLC) harboring PIK3CA mutation
    Oncol Res Treat. 2014;37 5: 65-65 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Scheffler M, Gardizi M, Bos M, Konig K, Michels S, Fassunke J, Heydt C, Kunstlinger H, Ihle MA, Ueckeroth F, Albus K, Serke M, Gerigk U, Schulte W, Topelt K, Nogova L, Zander T, Engel-Riedel W, Stoelben E, Ko YD, Randerath WJ, Kaminsky B, Panse J, Becker C, Hellmich M, Merkelbach-Bruse S, Buttner R, Heukamp LC, Wolf J
  • DDR2 mutations in non-small cell lung cancer (NSCLC): clinical, histological and genetic characteristics
    Oncol Res Treat. 2014;37 5: 66-66 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Scheffler M, Michels S, Gardizi M, Konig K, Merkelbach-Bruse S, Stamm K, Heukamp LC, Buttner R, Wolf J
  • Tumor infiltrating B-cells in primary cutaneous T-cell lymphoma correlate with disease progression and might represent a novel target for immunotherapy
    Oncol Res Treat. 2014;37 1: 31-31 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Theurich S, Schlaak M, Steguweit H, Heukamp LC, Wennhold K, Kurschat P, Shimabukuro-Vornhagen A, Schlosser H, Holtick U, Hallek M, Stadler R, von Bergwelt-Baildon M
  • [Epiphora with pressure-indolent swelling of the medial canthus].
    Ophthalmologe. 2014;111(8): 778-80 (Impact: liegt nicht vor, Typ=Editorial Material; Journal Article)
    Avgitidou G, Göbel H, Cursiefen C, Heindl LM
  • Histopathological assessment of tumour regression, nodal stage and status of resection margins determines prognosis in patients with oral squamous cell carcinoma treated with neoadjuvant radiochemotherapy.
    Oral Dis. 2014;20(3): e81-9 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Wedemeyer I, Kreppel M, Scheer M, Zöller JE, Büttner R, Drebber U
  • Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics.
    PLoS ONE. 2014;9(8): e104566 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Heydt C, Fassunke J, Künstlinger H, Ihle MA, König K, Heukamp LC, Schildhaus HU, Odenthal M, Büttner R, Merkelbach-Bruse S
  • The role of miRNA-34a as a prognostic biomarker for cirrhotic patients with portal
    hypertension receiving TIPS.
    PLoS ONE. 2014;9(7): e103779 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Jansen C, Eischeid H, Goertzen J, Schierwagen R, Anadol E, Strassburg CP, Sauerbruch T, Odenthal M, Trebicka J
  • The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells.
    PLoS ONE. 2014;9(4): e94931 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Kurakula K, Vos M, Otermin Rubio I, Marinkovi? G, Buettner R, Heukamp LC, Stap J, de Waard V, van Tiel CM, de Vries CJ
  • Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.
    PLoS ONE. 2014;9(2): e88718 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)
    Olthof NC, Speel EJ, Kolligs J, Haesevoets A, Henfling M, Ramaekers FC, Preuss SF, Drebber U, Wieland U, Silling S, Lam WL, Vucic EA, Kremer B, Klussmann JP, Huebbers CU
  • Extracapsular lymph node spread as a negative prognostic factor of adenocarcinoma of the pancreas and cancer of the papilla of vater.
    Pancreas. 2014;43(1): 64-8 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Prenzel KL, Hölscher AH, Drebber U, Bollschweiler E, Gutschow CA, Stippel DL, Mönig SP
  • Influence of formalin fixation on tissue dimensions in palatal tonsils.
    Pathol Res Pract. 2014;210(1): 59-61 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Vent J, Zimmermann Ch, Drebber U, Wedemeyer I, Eckel HE, Huettenbrink KB, Preuss SF
  • [Report of the working group on molecular pathology 2014].
    Pathologe. 2014;35 Suppl 2: 298-9 (Impact: liegt nicht vor, Typ=Journal Article; Journal Article)
    Dietmaier W, Merkelbach-Bruse S, Dahl E
  • Aregpkd - A European Arpkd Registry Study
    Pediatr Nephrol. 2014;29(9): 1835-1835 (Impact: liegt nicht vor, Typ=Meeting Abstract)
    Ebner K, Feldkoetter M, Bergmann C, Buettner R, Doyon A, Duzova A, Goebel H, Haffner D, Hero B, Hoppe B, Illig T, Jankauskiene A, Konrad M, Litwin M, Mekahli D, Ranchin B, Testa S, Weber LT, Zerres K, Schaefer F, Doetsch J, Liebau MC
  • Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.
    Sci Transl Med. 2014;6(252): 252ra123 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.)
    Zemojtel T, Köhler S, Mackenroth L, Jäger M, Hecht J, Krawitz P, Graul-Neumann L, Doelken S, Ehmke N, Spielmann M, Oien NC, Schweiger MR, Krüger U, Frommer G, Fischer B, Kornak U, Flöttmann R, Ardeshirdavani A, Moreau Y, Lewis SE, Haendel M, Smedley D, Horn D, Mundlos S, Robinson PN
  • Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma.
    Transl Oncol. 2014;7(2): 309-21 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Schütte U, Bisht S, Heukamp LC, Kebschull M, Florin A, Haarmann J, Hoffmann P, Bendas G, Buettner R, Brossart P, Feldmann G
  • Alterations of global histone H3K9 and H3K27 methylation levels in bladder cancer.
    Urol Int. 2014;93(1): 113-8 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Ellinger J, Bachmann A, Göke F, Behbahani TE, Baumann C, Heukamp LC, Rogenhofer S, Müller SC
  • Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers.
    Virchows Arch. 2014;465(3): 365-9 (Impact: liegt nicht vor, Typ=Letter; Letter; Research Support, Non-U.S. Gov't)
    Gevensleben H, Bossung V, Meindl A, Wappenschmidt B, de Gregorio N, Osorio A, Romero A, Buettner R, Markiefka B, Schmutzler RK
  • Pathohistological classification systems in gastric cancer: diagnostic relevance and prognostic value.
    World J Gastroenterol. 2014;20(19): 5679-84 (Impact: liegt nicht vor, Typ=Article; Journal Article)
    Berlth F, Bollschweiler E, Drebber U, Hoelscher AH, Moenig S

2013
  • Gastrointestinal stromal tumors with KIT exon 9 mutations: Update on genotype-phenotype correlation and validation of a high-resolution melting assay for mutational testing. 
Am J Surg Pathol. 2013;37(11): 1648-59  
Künstlinger H, Huss S, Merkelbach-Bruse S, Binot E, Kleine MA, Loeser H, Mittler J, Hartmann W, Hohenberger P, Reichardt P, Büttner R, Wardelmann E, Schildhaus HU 

  • A novel germline KIT mutation (p.L576P) in a family presenting with juvenile onset of multiple gastrointestinal stromal tumors, skin hyperpigmentations, and esophageal stenosis. 
Am J Surg Pathol. 2013;37(6): 898-905 
Neuhann TM, Mansmann V, Merkelbach-Bruse S, Klink B, Hellinger A, Höffkes HG, Wardelmann E, Schildhaus HU, Tinschert S 

  • Gastrointestinal stromal tumor of the rectum: results of surgical and multimodality therapy in the era of imatinib. 
Ann Surg Oncol. 2013;20(2): 586-92 
Jakob J, Mussi C, Ronellenfitsch U, Wardelmann E, Negri T, Gronchi A, Hohenberger P 

  • pT2 Adenocarcinoma of the esophagus: early or advanced cancer? 
Ann Thorac Surg. 2013;96(5): 1840-5 
Metzger R, Lorenz D, Gockel I, Origer J, Plum PS, Junginger T, Drebber U, Hansen T, Krümpelmann K, Fisseler-Eckhoff A, Lang H, Hölscher AH, Bollschweiler E 

  • Reproducibility of immunohistochemical scoring for epidermal growth factor receptor expression in non-small cell lung cancer: round robin test. 
Arch Pathol Lab Med. 2013;137(9): 1255-61 Rüschoff J, Kerr KM, Grote HJ, Middel P, von Heydebreck A, Alves VA, Baldus SE, Büttner R, Carvalho L, Fink L, Jochum W, Lo AW, López-Ríos F, Marx A, Molina TJ, Olszewski WT, Rieker RJ, Volante M, Thunnissen E, Wrba F, Celik I, Störkel S 

  • Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration 
BBA - MOL CELL RES. 2013;1833(5): 1190-1198 
Elfimova N, Sievers E, Eischeid H, Kwiecinski M, Noetel A, Hunt H, Becker D, Frommolt P, Quasdorff M, Steffen HM, Nurnberg P, Buttner R, Teufel A, Dienes HP, Drebber U, Odenthal M 

  • Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates liver fibrosis in mice 
BMC Gastroenterol. 2013;13: 1-9 
Huss S, Stellmacher C, Goltz D, Khlistunova I, Adam AC, Trebicka J, Kirfel J, Buttner R, Weiskirchen R 

  • CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. 
Blood. 2013;121(20): 4126-36 
Fedorchenko O, Stiefelhagen M, Peer-Zada AA, Barthel R, Mayer P, Eckei L, Breuer A, Crispatzu G, Rosen N, Landwehr T, Lilienthal N, Möllmann M, Montesinos-Rongen M, Heukamp L, Dürig J, Hallek M, Fingerle-Rowson G, Herling M 

  • Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis. 
Blood. 2013;122(10): 1779-88 
Peng WM, Maintz L, Allam JP, Raap U, Gütgemann I, Kirfel J, Wardelmann E, Perner S, Zhao W, Fimmers R, Walgenbach K, Oldenburg J, Schwartz LB, Novak N 
  • Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor. 
Blood. 2013;121(5): 812-21 
Reinart N, Nguyen PH, Boucas J, Rosen N, Kvasnicka HM, Heukamp L, Rudolph C, Ristovska V, Velmans T, Mueller C, Reiners KS, von Strandmann EP, Krause G, Montesinos-Rongen M, Schlegelberger B, Herling M, Hallek M, Fingerle-Rowson G 

  • Assessment of clinical parameters associated with mutational status in metastatic malignant melanoma: a single-centre investigation of 141 patients. 
Br J Dermatol. 2013;168(4): 708-16 
Schlaak M, Bajah A, Podewski T, Kreuzberg N, von Bartenwerffer W, Wardelmann E, Merkelbach-Bruse S, Büttner R, Mauch C, Kurschat P 

  • Therapeutic strategies in male breast cancer: Clinical implications of chromosome 17 gene alterations and molecular subtypes. 
Breast. 2013;22(6): 1066-71 
Schildhaus HU, Schroeder L, Merkelbach-Bruse S, Binot E, Büttner R, Kuhn W, Rudlowski C 
  • The Oncological Emergency Case: Paraneoplastic Hypoglycemia in Metastatic Breast Cancer - Case Report and Brief Review of the Literature 
Breast Care OR. 2013;8(5): 368-370 Richters L, Ortmann M, Faust M, Kramer S, Mallmann P, Harbeck N, Rhiem K 
  • [Biomarker analysis from a pathologist's view. Founding the rationale for personalised treatment of lung cancer]. 
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013;56(11): 1502-8 
Buettner R, Heydt C 

  • SRC signaling is crucial in the growth of synovial sarcoma cells. 
Cancer Res. 2013;73(8): 2518-28 
Michels S, Trautmann M, Sievers E, Kindler D, Huss S, Renner M, Friedrichs N, Kirfel J, Steiner S, Endl E, Wurst P, Heukamp L, Penzel R, Larsson O, Kawai A, Tanaka S, Sonobe H, Schirmacher P, Mechtersheimer G, Wardelmann E, Büttner R, Hartmann W 

  • Potential complications of transcatheter aortic valve implantation (TAVI)-an autopsy perspective. 
Cardiovasc Pathol. 2013;22(5): 319-23 Loeser H, Wittersheim M, Puetz K, Friemann J, Buettner R, Fries JW 

  • Strong ERG Positivity in Papillary Intralymphatic Angioendothelioma of the Testis of a 24-Year-Old Male: A Case Report. 
Case Report Pathol. 2013;2013: 531479 Schultheis AM, Sandmann M, Steurer S 
  • Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma. 
Cell Death Dis. 2013;4: e586 
Kocak H, Ackermann S, Hero B, Kahlert Y, Oberthuer A, Juraeva D, Roels F, Theissen J, Westermann F, Deubzer H, Ehemann V, Brors B, Odenthal M, Berthold F, Fischer M 

  • Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6R? signaling. 
Cell Rep. 2013;4(4): 669-80 Gruber S, Straub BK, Ackermann PJ, Wunderlich CM, Mauer J, Seeger JM, Büning H, Heukamp L, Kashkar H, Schirmacher P, Brüning JC, Wunderlich FT 
  • Ubiquitin C-Terminal Hydrolase-L1 Potentiates Cancer Chemosensitivity by Stabilizing NOXA 
Cell Reports. 2013;3(3): 881-891 
Brinkmann K, Zigrino P, Witt A, Schell M, Ackermann L, Broxtermann P, Schull S, Andree M, Coutelle O, Yazdanpanah B, Seeger JM, Klubertz D, Drebber U, Hacker UT, Kronke M, Mauch C, Hoppe T, Kashkar H 

  • Telmisartan Plus Propranolol Improves Liver Fibrosis and Bile Duct Proliferation in the PSC-Like Abcb4(-/-) Mouse Model. 
Dig Dis Sci. 2013;58(5): 1271-81 
Mende S, Schulte S, Strack I, Hunt H, Odenthal M, Pryymachuck G, Quasdorff M, Demir M, Nierhoff D, Dienes HP, Goeser T, Steffen HM, Töx U 

  • Fibroblast growth factor receptor 1 as a putative therapy target in colorectal cancer. 
Digestion. 2013;88(3): 172-81 Göke F, Göke A, von Mässenhausen A, Franzen A, Sharma R, Kirsten R, Böhm D, Kristiansen G, Stenzinger A, Wynes M, Hirsch FR, Weichert W, Heasley L, Buettner R, Perner S 

  • Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome. 
Dtsch Arztebl Int. 2013;110(3): 32-8 Steinke V, Engel C, Büttner R, Schackert HK, Schmiegel WH, Propping P 

  • [53-year-old patient with progressive dyspnea]. 
Dtsch Med Wochenschr. 2013;138(28-29): 1463-4 
Michels G, Er F, Drebber U, Pfister R 

  • High throughput parallel amplicon sequencing of common driver mutations from FFPE lung cancer samples in molecular pathological routine diagnostics for a regional health care provider network 
Eur J Cancer. 2013;49 2: S813-S813 Heukamp L, Konig K, Peifer M, Stamm K, Bos M, Vollbrecht C, Merkelbach-Buse S, Henkel T, Wolf J, Buettner R 

  • Differential expression and in vivo secretion of the antimicrobial peptides psoriasin (S100A7), RNase 7, human beta-defensin-2 and -3 in healthy human skin. 
Exp Dermatol. 2013;22(5): 364-6 Wittersheim M, Cordes J, Meyer-Hoffert U, Harder J, Hedderich J, Gläser R 
  • Hyperoxaluria and systemic oxalosis: an update on current therapy and future directions. 
Expert Opin Investig Drugs. 2013;22(1): 117-29 Beck BB, Hoyer-Kuhn H, Göbel H, Habbig S, Hoppe B 

  • Whole Exome Sequencing Revealed Putative Driver Mutations in Esophageal Cancer 
Gastroenterology. 2013;144 1(5): S1089-S1089 Grimminger PP, Peifer M, Thomas R, Maus MK, Brabender J, Holscher AH, Buttner R, Odenthal M 
  • [Soft tissue tumors of the head and neck region]. 
HNO. 2013;61(11): 928-36 Laffers W, Stöhr G, Göke F, Wardelmann E, Keiner S, Zipfel M, Schüller H, Gerstner AO 

  • [Bleeding tumor of the auricle]. 
HNO. 2013;61(10): 875-7 Meyer MF, Wedemeyer I, Beutner D 

  • [Schwannoma in the epipharynx : A rare differential diagnosis]. 
HNO. 2013;61(5): 425-8 Meyer MF, Anagiotos A, Lüers JC, Löser H, Wardelmann E, Beutner D 

  • Multiple craniocervical chordomas presenting as a parapharyngeal mass. 
Head Neck. 2013;35(11): E325-7 
Anagiotos A, Preuss SF, Drebber U, Jumah MD 

  • Stage grouping in tumors of the ethmoid sinuses and the nasal cavity using the sixth edition of the UICC classification of malignant tumors. 
Head Neck. 2013;35(2): 257-64 
Kreppel M, Scheer M, Beutner D, Drebber U, Semrau R, Zöller JE, Guntinas-Lichius O 

  • Prognostic impact of human papillomavirus status, survivin, and epidermal growth factor receptor expression on survival in patients treated with radiochemotherapy for very advanced nonresectable oropharyngeal cancer. 
Head Neck. 2013;35(9): 1339-44 
Semrau R, Duerbaum H, Temming S, Huebbers C, Stenner M, Drebber U, Klussmann JP, Müller RP, Preuss SF 

  • p16 expression in carcinoma of unknown primary: diagnostic indicator and prognostic marker. 
Head Neck. 2013;35(11): 1521-6 Vent J, Haidle B, Wedemeyer I, Huebbers C, Siefer O, Semrau R, Preuss SF, Klussmann J 

  • Mucinous cystic neoplasm or non-parasitic liver cyst? - A challenging diagnosis. 
Hepatogastroenterology. 2013;60(123): 585-9 Wahba R, Kleinert R, Dieplinger G, Bangard C, Drebber U, Hölscher AH, Stippel DL 

  • Vital staining of blood vessels and bile ducts with carboxyfluorescein diacetate succinimidyl ester: a novel tool for isolation of cholangiocytes. 
Histol Histopathol. 2013;28(8): 1013-20 
Pryymachuk G, Polykandriotis E, Schievenbusch S, Arkudas A, Nierhoff D, Curth HM, Odenthal M, Horch RE, Neiss WF, Goeser T, Steffen HM, Toex U 

  • ?-catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid-type fibromatosis. 
Histopathology. 2013;62(2): 294-304 Huss S, Nehles J, Binot E, Wardelmann E, Mittler J, Kleine MA, Künstlinger H, Hartmann W, Hohenberger P, Merkelbach-Bruse S, Buettner R, Schildhaus HU 

  • Fibroblast growth factor receptor 1 gene amplification in pancreatic ductal adenocarcinoma. 
Histopathology. 2013;63(2): 157-66 Lehnen NC, von Mässenhausen A, Kalthoff H, Zhou H, Glowka T, Schütte U, Höller T, Riesner K, Boehm D, Merkelbach-Bruse S, Kirfel J, Perner S, Gütgemann I 

  • Follicle-stimulating hormone receptor expression in soft tissue sarcomas. 
Histopathology. 2013;63(1): 29-35 
Renner M, Goeppert B, Siraj MA, Radu A, Penzel R, Wardelmann E, Lehner B, Ulrich A, Stenzinger A, Warth A, Vogel MN, Weichert W, Schirmacher P, Mechtersheimer G, Ghinea N 

  • MicroRNA profiling in locally advanced esophageal cancer indicates a high potential of miR-192 in prediction of multimodality therapy response. 
Int J Cancer. 2013;133(10): 2454-63 
Odenthal M, Bollschweiler E, Grimminger PP, Schröder W, Brabender J, Drebber U, Hölscher AH, Metzger R, Vallböhmer D 

  • Lung cancer. Molecular pathology and personalized therapy 
Internist. 2013;54(2): 179-+ 
Schultheis A, Wolf J, Buttner R
  • Impact of clinical and lesion characteristics on the results of MR-guided wire localizations of the breast using an open 1.0-T MRI system. 
Invest Radiol. 2013;48(6): 445-51 
Krug KB, Ulhaas A, Hellmich M, Schwabe H, Krämer S, Malter W, Müller D, Markiefka B, Maintz D 
  • Stepwise combination of simple noninvasive fibrosis scoring systems increases diagnostic accuracy in nonalcoholic fatty liver disease. 
J Clin Gastroenterol. 2013;47(8): 719-26 Demir M, Lang S, Nierhoff D, Drebber U, Hardt A, Wedemeyer I, Schulte S, Quasdorff M, Goeser T, Töx U, Steffen HM 

  • Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. 
J Clin Invest. 2013;123(4): 1732-40 Chatterjee S, Heukamp LC, Siobal M, Schöttle J, Wieczorek C, Peifer M, Frasca D, Koker M, König K, Meder L, Rauh D, Buettner R, Wolf J, Brekken RA, Neumaier B, Christofori G, Thomas RK, Ullrich RT 

  • Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer (vol 123, pg 1732, 2013) 
J Clin Invest. 2013;123(7): 3183-3183 
Chatterjee S, Heukamp LC, Siobal M, Schottle J, Wieczorek C, Peifer M, Frasca D, Koker M, Koenig K, Meder L, Rauh D, Buettner R, Wolf J, Brekken RA, Neumaier B, Christofori G, Thomas RK, Ullrich RT 

  • Lessons learned from lung cancer genomics: the emerging concept of individualized diagnostics and treatment. 
J Clin Oncol. 2013;31(15): 1858-65 Buettner R, Wolf J, Thomas RK 

  • Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues. 
J Clin Pathol. 2013;66(9): 803-6 
Becker K, Vollbrecht C, Koitzsch U, Koenig K, Fassunke J, Huss S, Nuernberg P, Heukamp LC, Buettner R, Odenthal M, Altmueller J, Merkelbach-Bruse S 

  • The role of clinical versus histopathological staging in patients with advanced oral squamous cell carcinoma treated with neoadjuvant radiochemotherapy followed by radical surgery. 
J Craniomaxillofac Surg. 2013;41(1): 22-7 Kreppel M, Dreiseidler T, Rothamel D, Eich HT, Drebber U, Zöller JE, Scheer M 

  • Tumor-infiltrating B-Cells in primary cutaneous T-Cell Lymphoma: Progression Markers and potential Therapeutic Target 
J Dtsch Dermatol Ges. 2013;11(9): 919-919 
Schlaak M, Theurich S, Steguweit H, Heukamp L, Kurschat P, Rabenhorst A, Hartmann K, Hallek M, Stadler R, von Bergwelt-Baildon M 

  • BRAF-positive metastatic malignant Melanoma (MM) on the Bottom of a Giant Pigmented Naevus; no Response to Vemurafenib 
J Dtsch Dermatol Ges. 2013;11(9): 951-951 
Schlosser R, Patzold S, Buttner R, Rosch A, Kaufmann R, Meissner M 

  • STEPWISE COMBINATION OF SIMPLE NON-INVASIVE FIBROSIS SCORING SYSTEMS INCREASES DIAGNOSTIC ACCURACY IN NON-ALCOHOLIC FATTY LIVER DISEASE 
J Hepatol. 2013;58 1: S535-S535 Demir M, Lang S, Nierhoff D, Drebber U, Wedemeyer I, Goeser T, Tox U, Steffen HM 

  • miR-101 IN STEATOSIS AND STEATOHEPATITIS OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) 
J Hepatol. 2013;58 1: S508-S508 Elfimova N, Ommer K, Schlattjan M, Sowa JP, Wedemeyer I, Vantler M, Dienes HP, Canbay A, Odenthal M 
  • COMPLEX REGULATION OF THE microRNA-29a/b GENE BY TGF-beta SIGNALING 
J Hepatol. 2013;58 1: S456-S456 
Huang J, Elfimova N, Noetel A, Eischeid H, Dienes HP, Odenthal M 

  • Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion. 
J Hepatol. 2013;59(3): 528-35 Höchst B, Schildberg FA, Sauerborn P, Gäbel YA, Gevensleben H, Goltz D, Heukamp LC, Türler A, Ballmaier M, Gieseke F, Müller I, Kalff J, Kurts C, Knolle PA, Diehl L 

  • Intrahepatic IL-8 producing Foxp3?CD4? regulatory T cells and fibrogenesis in chronic hepatitis C. 
J Hepatol. 2013;59(2): 229-35 
Langhans B, Krämer B, Louis M, Nischalke HD, Hüneburg R, Staratschek-Jox A, Odenthal M, Manekeller S, Schepke M, Kalff J, Fischer HP, Schultze JL, Spengler U 

  • HCV INFECTION REPROGRAMS THE HEPATIC GLUCOSE AND GLUTAMINE METABOLISM 
J Hepatol. 2013;58 1: S474-S474 Levy P, Michelet M, Brault C, Salle A, Parent R, Durantel D, Elena-Herrmann B, Steffen HM, Zoulim F, Odenthal M, Bartosch B 

  • Next generation sequencing of the Ago2 interacting transcriptome identified chemokine family members as novel targets of neuronal microRNAs in hepatic stellate cells. 
J Hepatol. 2013;58(2): 335-41 Noetel A, Elfimova N, Altmüller J, Becker C, Becker D, Lahr W, Nürnberg P, Wasmuth H, Teufel A, Büttner R, Dienes HP, Odenthal M 

  • Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis. 
J Hepatol. 2013;58(2): 234-9 
Trebicka J, Anadol E, Elfimova N, Strack I, Roggendorf M, Viazov S, Wedemeyer I, Drebber U, Rockstroh J, Sauerbruch T, Dienes HP, Odenthal M 

  • Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT). 
J Mol Med. 2013;91(6): 739-48 Bartram MP, Höhne M, Dafinger C, Völker LA, Albersmeyer M, Heiss J, Göbel H, Brönneke H, Burst V, Liebau MC, Benzing T, Schermer B, Müller RU 

  • Integration of Human Papillomavirus Type 16 in Oropharyngeal Squamous Cell Carcinomas does not Invariably Result in High Levels of Viral Gene Transcripts 
J Pathol. 2013;229 1: S17-S17 
Speel EJM, Olthof NC, Huebbers CU, Kolligs J, Haesevoets A, Henfling M, Ramaekers FCS, Preuss SF, Drebber U, Lam W, Vucic E, Kremer B, Klussmann JP 

  • Podoplanin expression in cutaneous head and neck squamous cell carcinoma-prognostic value and clinicopathologic implications. 
J Surg Oncol. 2013;107(4): 376-83 
Kreppel M, Krakowezki A, Kreppel B, Drebber U, Wedemeyer I, Mauch C, Zöller JE, Scheer M 

  • Reduced folate carrier and folylpolyglutamate synthetase, but not thymidylate synthase predict survival in pemetrexed-treated patients suffering from malignant pleural mesothelioma. 
J Thorac Oncol. 2013;8(5): 644-53 Mairinger F, Vollbrecht C, Halbwedl I, Hatz M, Stacher E, Gülly C, Quehenberger F, Stephan-Falkenau S, Kollmeier J, Roth A, Mairinger T, Popper H 

  • The issue of studies evaluating biomarkers which predict outcome after pemetrexed-based chemotherapy in malignant pleural mesothelioma. 
J Thorac Oncol. 2013;8(8): e80-2 Mairinger F, Vollbrecht C, Mairinger T, Popper H 

  • Histone methylation defines an epigenetic entity in penile squamous cell carcinoma. 
J Urol. 2013;189(3): 1117-22 Rogenhofer S, Miersch H, Göke F, Kahl P, Wieland WF, Hofstädter F, Kristiansen G, von Ruecker A, Müller SC, Ellinger J 
  • Targeted Therapy for Neuroblastoma: ALK Inhibitors. 
Klin Padiatr. 2013;225(6): 303-308 
Schulte JH, Schulte S, Heukamp LC, Astrahantseff K, Stephan H, Fischer M, Schramm A, Eggert A 

  • A Subset of Gastrointestinal Stromal Tumors Previously Regarded as Wildtype GISTs Carries Sporadic Activating Mutations in the Extracellular Ligand Binding Domain of KIT(Exon 8, p.D419del) 
Lab Invest. 2013;93 1: 19A-20A 
Schildhaus HU, Huss S, Merkelbach-Bruse S, Kleine M, Helen K, Buttner R, Wardelmann E 

  • The laparoscopic approach for radiofrequency ablation of hepatocellular carcinoma-indication, technique and results. 
Langenbecks Arch Surg. 2013;398(1): 47-53 
Herbold T, Wahba R, Bangard C, Demir M, Drebber U, Stippel DL 

  • Complete metabolic response in a patient with repeatedly relapsed non-small cell lung cancer harboring ROS1 gene rearrangement after treatment with crizotinib. 
Lung Cancer. 2013;81(1): 142-3 Bos M, Gardizi M, Schildhaus HU, Heukamp LC, Geist T, Kaminsky B, Zander T, Nogova L, Scheffler M, Dietlein M, Kobe C, Holstein A, Maintz D, Büttner R, Wolf J 

  • Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): Results of a multi-centre ALK-testing 
Lung Cancer. 2013;81(2): 200-206 Laffert MV, Warth A, Penzel R, Schirmacher P, Jonigk D, Kreipe H, Schildhaus HU, Merkelbach-Bruse S, Buttner R, Reu S, Kerler R, Jung A, Kirchner T, Wolfel C, Petersen I, Rodriguez R, Jochum W, Bartsch H, Fisseler-Eckhoff A, Berg E, Lenze D, Dietel M, Hummel M 

  • A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del). 
Mod Pathol. 2013;26(7): 1004-12 
Huss S, Künstlinger H, Wardelmann E, Kleine MA, Binot E, Merkelbach-Bruse S, Rüdiger T, Mittler J, Hartmann W, Büttner R, Schildhaus HU 

  • A Subset of Gastrointestinal Stromal Tumors Previously Regarded as Wildtype GISTs Carries Sporadic Activating Mutations in the Extracellular Ligand Binding Domain of KIT(Exon 8, p.D419del) 
Mod Pathol. 2013;26 2: 19A-20A 
Schildhaus HU, Huss S, Merkelbach-Bruse S, Kleine M, Helen K, Buttner R, Wardelmann E 

  • Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung. 
Mod Pathol. 2013;26(11): 1468-77 Schildhaus HU, Deml KF, Schmitz K, Meiboom M, Binot E, Hauke S, Merkelbach-Bruse S, Büttner R 

  • Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. 
Nat Immunol. 2013;14(6): 574-83 
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA 

  • MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells. 
Oncogene. 2013;32(8): 1059-65 Schulte JH, Lindner S, Bohrer A, Maurer J, De Preter K, Lefever S, Heukamp L, Schulte S, Molenaar J, Versteeg R, Thor T, Künkele A, Vandesompele J, Speleman F, Schorle H, Eggert A, Schramm A 

  • Genomic analysis of small cell lung cancer - new therapeutic options? 
Oncology. 2013;19(11): 958-961Heukamp LC, Buttner R 

  • Overall survival of ALK translocation positive NSCLC patients treated with and without crizotinib. A retrospective analysis within the Network Genomic Medicine 
Onkologie. 2013;36 7: 28-29 Bos M, Gardizi M, Heukamp L, Nogova L, Merkelbach-Bruhse S, Konig K, Zander T, Schildhaus HU, Fricke R, Krieg V, Scheffler M, Serke M, Schnell R, Schulz H, Topelt K, Panse J, Schmitz S, Severin K, Steinmetz T, Gerigk U, Brettner S, Hecker E, Reiser M, Katay I, Kaufmann T, Ko YD, Buchenroth M, Kruis W, Schlesinger A, Laskowski U, Maintz C, Vogt J, Randerath WJ, Konrad F, Hekmat K, Kruger S, Kambartel K, Galetke W, Hunerliturkoglu AN, Thomas R, Buttner R, Wolf J, Netzwerk Genomische Med 

  • Current development of the Network Genomic Medicine in lung cancer 
Onkologie. 2013;36 7: 177-177 Bos M, Heukamp L, Gardizi M, Konig K, Merkelbach-Bruhse S, Zander T, Scheffler M, Albus K, Schildhaus HU, Fassunke J, Kunstlinger H, Kleine M, Binot E, Nogova L, Mattonet C, Serke M, Panse J, Schnell R, Schulz H, Topelt K, Schlesinger A, Kruger S, Kambartel K, Reiser M, Behringer D, Gerigk U, Schulte W, Diet F, Randerath WJ, Brettner S, Ko YD, Buchenroth M, Benz J, Severin K, Schmitz S, Steinmetz T, Mainka D, Dietze L, Kaufmann T, Konrad F, Hekmat K, Thomas R, Buttner R, Wolf J, Netzwerk Genomische Med 

  • Overcoming EGFR-TKI resistance in EGFR-mutated lung cancer 
Onkologie. 2013;36 7: 30-30 Gardizi M, Scheffler M, Bos M, Geist T, Heukamp L, Nogova L, Topelt K, Fernandez-Cuesta L, Culmann H, Kaminsky B, Panse J, Becker C, Mattonet C, Serke M, Schmitz S, Schnell R, Galetke W, Hekmat K, Buttner R, Wolf J 

  • TRY: A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small-cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation 
Onkologie. 2013;36 7: 30-30 Nogova L, Gardizi M, Bos MCA, Scheffler M, Papachristou I, Wompner C, Heukamp LC, Schildhaus HU, Fuhr U, Sos ML, Eberhardt W, Wiesweg M, Schmid KW, Schuler M, Thomas RK, Buttner R, Wolf J 

  • Yes-associated protein (YAP) contributes to enhanced tumorigenicity and an invasive phenotype in ccRCC cell lines via interaction with the endothelin axis and c-Myc 
Onkologie. 2013;36 7: 75-75 
Schutte U, Bisht S, Haarmann J, Kebschull M, Heukamp LC, Buettner R, Brossart P, Feldmann G 
  • Tumor infiltrating B cells in primary cutaneous T-cell Lymphoma correlate with disease progression and might represent a potential therapeutic target 
Onkologie. 2013;36 7: 196-196 
Theurich S, Schlaak M, Steguweit H, Heukamp LC, Wennhold K, Kurschat P, Rabenhorst A, Hartmann K, Schlosser H, Shimabukuro-Vornhagen A, Hotick U, Hallek M, Stadler R, von Bergwelt-Baildon M 

  • Comparison of TNM-based stage grouping versus UICC/AJCC stage grouping (7th edition) in malignant parotid gland tumors. 
Oral Oncol. 2013;49(9): 903-10 
Kreppel M, Scheer M, Meyer M, Stenner M, Wedemeyer I, Drebber U, Semrau R, Odenthal M, Zöller JE, Guntinas-Lichius O, Büttner R, Beutner D 

  • Kinetics of miR-122 expression in the liver during acute HCV infection. 
PLoS ONE. 2013;8(10): e76501 Choi Y, Dienes HP, Krawczynski K 

  • NIKEI: a new inexpensive and non-invasive scoring system to exclude advanced fibrosis in patients with NAFLD. 
PLoS ONE. 2013;8(3): e58360 Demir M, Lang S, Schlattjan M, Drebber U, Wedemeyer I, Nierhoff D, Kaul I, Sowa J, Canbay A, Töx U, Steffen HM 
  • Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis. 
PLoS ONE. 2013;8(2): e57207 
Huebbers CU, Preuss SF, Kolligs J, Vent J, Stenner M, Wieland U, Silling S, Drebber U, Speel EJ, Klussmann JP 

  • Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]. 
PLoS ONE. 2013;8(5): e64102 Kelly L, Bryan K, Kim SY, Janeway KA, Killian JK, Schildhaus HU, Miettinen M, Helman L, Meltzer PS, van de Rijn M, Debiec-Rychter M, O'Sullivan M, NIH Pediatric and Wild-Type GIST Clinic , Antonescu C, Demetri G, Duensing A, George S, Jose-Dizon JM, Khan J, xKummar J, LaQuaglia M, Lodish M, MacArthur G, Pappo A, Raygada M, Schiffman J, Stratakis CA, Trent J, von Mehren M, Wright J 
  • Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model. 
PLoS ONE. 2013;8(3): e57996 König K, Meder L, Kröger C, Diehl L, Florin A, Rommerscheidt-Fuss U, Kahl P, Wardelmann E, Magin TM, Buettner R, Heukamp LC 

  • SNAI1-mediated epithelial-mesenchymal transition confers chemoresistance and cellular plasticity by regulating genes involved in cell death and stem cell maintenance. 
PLoS ONE. 2013;8(6): e66558 
Lim S, Becker A, Zimmer A, Lu J, Buettner R, Kirfel J 

  • Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29. 
PLoS ONE. 2013;8(1): e55786 Mannaerts I, Eysackers N, Onyema OO, Van Beneden K, Valente S, Mai A, Odenthal M, van Grunsven LA 

  • Prognostic impact of [18F]fluorothymidine and [18F]fluoro-D-glucose baseline uptakes in patients with lung cancer treated first-line with erlotinib. 
PLoS ONE. 2013;8(1): e53081 
Scheffler M, Zander T, Nogova L, Kobe C, Kahraman D, Dietlein M, Papachristou I, Heukamp L, Büttner R, Boellaard R, Lammertsma AA, Querings S, Stoelben E, Engel-Riedel W, Neumaier B, Wolf J 

  • FFPE tissue as a feasible source for gene expression analysis--a comparison of three reference genes and one tumor marker. 
Pathol Res Pract. 2013;209(12): 784-9 Walter RF, Mairinger FD, Wohlschlaeger J, Worm K, Ting S, Vollbrecht C, Kurt Werner S, Hager T 

  • Report on the General Assembly of the Working Group on Molecular Pathology during the 97th Annual Meeting of the German Society for Pathology (DGP) in Heidelberg 
Pathologe. 2013;34 2: 295-296 Dietmaier W, Penzel R, Merkelbach-Bruse S 

  • [Current challenges in pathology - practical solutions for commonly occurring problems: Introduction to the 49th symposium of the German division of the International Academy of Pathology, 22-24 February 2013, in Bonn]. 
Pathologe. 2013;34(1): 8 Heydt C, Büttner R 
  • [Massive ovarian edema in a 13-year-old girl]. 
Pathologe. 2013;34(6): 563-5 Sailer V, Huss S, Wardelmann E, Müller AM 

  • [Molecular pathology of the lungs. New perspectives by next generation sequencing]. 
Pathologe. 2013;34(1): 16-24 Vollbrecht C, König K, Heukamp L, Büttner R, Odenthal M 

  • First evidence of NPHP9 null-mutations in humans resulting in renal-pancreato-hepatic dysplasia 
Pediatr Nephrol. 2013;28(8): 1539-1539 Habbig S, Frank V, Bartram M, Goebel H, Benzing T, Schermer B, Bergmann C 

  • A Genomics-Based Classification of Human Lung Tumors 
Sci Transl Med. 2013;5(209): 209ra153- Seidel D, Zander T, Heukamp LC, Peifer M, Bos M, Fernandez-Cuesta L, Leenders F, Lu X, Ansen S, Gardizi M, Nguyen C, Berg J, Russell P, Wainer Z, Schildhaus HU, Rogers TM, Solomon B, Pao W, Carter SL, Getz G, Hayes DN, Wilkerson MD, Thunnissen E, Travis WD, Perner S, Wright G, Brambilla E, Buttner R, Wolf J, Thomas RK, Gabler F, Wilkening I, Muller C, Dahmen I, Menon R, Konig K, Albus K, Merkelbach-Bruse S, Fassunke J, Schmitz K, Kuenstlinger H, Kleine MA, Binot E, Querings S, Altmuller J, Bossmann I, Numberg P, Schneider PM, Bogus M, Buttner R, Perner S, Russell P, Thunnissen E, Travis WD, Brambilla E, Soltermann A, Moch H, Brustugun OT, Solberg S, Lund-Iversen M, Helland A, Muley T, Hoffmann H, Schnabel PA, Chen Y, Groen H, Timens W, Sietsma H, Clement JH, Weder W, Sanger J, Stoelben E, Ludwig C, Engel-Riedel W, Smit E, Heideman DAM, Snijders PJF, Nogova L, Sos ML, Mattonet C, Topelt K, Scheffler M, Goekkurt E, Kappes R, Kruger S, Kambartel K, Behringer D, Schulte W, Galetke W, Randerath W, Heldwein M, Schlesinger A, Serke M, Hekmat K, Frank KF, Schnell R, Reiser M, Hunerliturkoglu AN, Schmitz S, Meffert L, Ko YD, Litt-Lampe M, Gerigk U, Fricke R, Besse B, Brambilla C, Lantuejoul S, Lorimier P, Moro-Sibilot D, Cappuzzo F, Ligorio C, Damiani S, Field JK, Hyde R, Validire P, Girard P, Muscarella LA, Fazio VM, Hallek M, Soria JC, Carter SL, Getz G, Hayes DN, Wilkerson MD, Achter V, Lang U, Seidel D, Zander T, Heukamp LC, Peifer M, Bos M, Pao W, Travis WD, Brambilla E, Buttner R, Wolf J, Thomas RK, CLCGP , NGM 

  • CD30-targeted therapy with brentuximab vedotin and DLI in a patient with T-cell posttransplantation lymphoma: induction of clinical remission and cellular immunity. 
Transplantation. 2013;96(3): e16-8 
Theurich S, Wennhold K, Wedemeyer I, Rothe A, Hübel K, Shimabukuro-Vornhagen A, Holtick U, Hallek M, Scheid C, von Bergwelt-Baildon M 

  • A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice. 
Vaccine. 2013;31(8): 1197-203 Buchmann P, Dembek C, Kuklick L, Jäger C, Tedjokusumo R, von Freyend MJ, Drebber U, Janowicz Z, Melber K, Protzer U
2012
  • Thymoma--an important differential diagnosis of mediastinal tumours. 
    Acta Clin Belg. 2012;67(4): 304-5 
    Michels G, Drebber U, Pfister R 
  • MicroRNA 15a, inversely correlated to PKC?, is a potential marker to differentiate between benign and malignant renal tumors in biopsy and urine samples. 
    Am J Pathol. 2012;180(5): 1787-97 von Brandenstein M, Pandarakalam JJ, Kroon L,Loeser H, Herden J, Braun G, Wendland K, Dienes HP, Engelmann U, Engelmann U, Fries JW 
  • The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes. 
    Am J Physiol Gastrointest Liver Physiol. 2012;302(8): G873-87 Wojtalla A, Herweck F, Granzow M, Klein S, Trebicka J, Huss S, Lerner R, Lutz B, Schildberg FA, Knolle PA, Sauerbruch T, Singer MV, Zimmer A, Siegmund SV 
  • Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. 
    Am J Physiol Renal Physiol. 2012;303(10): F1473-85 
    Brähler S, Ising C, Hagmann H, Rasmus M, Hoehne M, Kurschat C, Kisner T, Goebel H, Shankland S, Addicks K, Thaiss F, Schermer B, Schermer B, Pasparakis M, Benzing T, Benzing T, Brinkkoetter PT 
  • Optimal lymph node harvest in rectal cancer (UICC stages II and III) after preoperative 5-FU-based radiochemotherapy. Acetone compression is a new and highly efficient method. 
    Am J Surg Pathol. 2012;36(2): 202-13 Gehoff A, Basten O, Sprenger T, Conradi LC, Bismarck C, Bandorski D, Merkelbach-Bruse S, Schneider-Stock R, Stoehr R, Wirtz RM, Kitz J, Müller A, Hartmann A, Becker H, Ghadimi BM, Liersch T, Rüschoff J 
  • Gastrointestinal stromal tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up 
    Ann Oncol. 2012;23 7: 49-55 
    ESMO European Sarcoma Network Work ESMO 
  • Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up 
    Ann Oncol. 2012;23 7: 92-99 
    ESMO European Sarcoma Network Working Grp ESMO
  • GASTROINTESTINAL STROMAL TUMORS OF THE STOMACH WITH KIT EXON 9 MUTATIONS MOSTLY PRESENT WITH A FAVORABLE PROGNOSIS 
    Ann Oncol. 2012;23 9: 481-481 
    Wardelmann E, Loser H, Jeske W, Merkelbach-Bruse S, Hohenberger P, Reichardt P, Bauer S, Buettner R, Huss S, Schildhaus H 
  • ANAPLASTIC LYMPHOMA KINASE (ALK) GENE REARRANGEMENT IN NON-SMALL CELL LUNG CANCER (NSCLC): RESULTS OF THE FIRST INTERN ROUND ROBIN PANEL TESTING (8 INSTITUTES FROM GERMANY AND SWITZERLAND) 
    Ann Oncol. 2012;23 9: 394-394 
    von Laffert M, Schirmacher P, Kreipe H, Buttner R, Petersen I, Jochum W, Dietel M, Hummel M 
  • Hereditary esophageal-vulvar syndrome. 
    Ann Thorac Surg. 2012;94(3): e65-7 Hoelscher AC, Hoelscher AH, Drebber U, Bludau M, Schroeder W 
  • Enhanced expression of peroxisome proliferate-activated receptor gamma (PPAR-?) in advanced prostate cancer. 
    Anticancer Res. 2012;32(8): 3479-83 Rogenhofer S, Ellinger J, Kahl P, Stoehr C, Hartmann A, Engehausen D, Wieland WF, Müller SC, Hofstädter F, Walter B 
  • Decreased levels of histone H3K9me1 indicate poor prognosis in patients with renal cell carcinoma. 
    Anticancer Res. 2012;32(3): 879-86 Rogenhofer S, Kahl P, Holzapfel S, von Ruecker A, Mueller SC, Ellinger J 
  • Anti-HDV immunoglobulin M testing in hepatitis delta revisited: correlations with disease activity and response to pegylated interferon-?2a treatment. 
    Antivir Ther. 2012;17(2): 305-12 
    Mederacke I, Yurdaydin C, Dalekos GN, Bremer B, Erhardt A, Cakaloglu Y, Yalcin K, Gurel S, Zeuzem S, Zachou K, Bozkaya H, Dienes HP, Manns MP, Wedemeyer H, Hep-Net/International Delta Hepatitis Study Group 
  • Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast. 
    BMC Clin Pathol. 2012;12: 13 
    Serce N, Gnatzy A, Steiner S, Lorenzen H, Kirfel J, Buettner R 
  • Alterations of global histone H4K20 methylation during prostate carcinogenesis 
    BMC Urol. 2012;12: 1-6 
    Behbahani TE, Kahl P, von der Gathen J, Heukamp LC, Baumann C, Gutgemann I, Walter B, Hofstadter F, Bastian PJ, von Ruecker A, Muller SC, Rogenhofer S, Ellinger J 
  • Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components. 
    Biochem Biophys Res Commun. 2012;421(4): 665-70 Janzer A, Lim S, Fronhoffs F, Niazy N, Buettner R, Kirfel J 
  • Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis). 
    Blood. 2012;120(26): 5128-33; quiz 5252 
    Barbui T, Finazzi G, Carobbio A, Thiele J, Passamonti F, Rumi E, Ruggeri M, Rodeghiero F, Randi ML, Bertozzi I, Gisslinger H, Buxhofer-Ausch V, De Stefano V, Betti S, Rambaldi A, Vannucchi AM, Tefferi A 
  • Mast cells play a protumorigenic role in primary cutaneous lymphoma 
    Blood. 2012;120(10): 2042-2054 
    Rabenhorst A, Schlaak M, Heukamp LC, Forster A, Theurich S, von Bergwelt-Baildon M,Buttner R, Kurschat P, Mauch C, Roers A, Hartmann K 
  • Filariasis of the Axilla in a Patient Returning from Travel Abroad: A Case Report 
    Breast Care. 2012;7(6): 487-489 
    Roethlisberger M, Wuerstlein R, Majores M, Muller-Stover I, Seitz HM, Rhiem K, Kraemer S, Mallmann P, Buttner R, Harbeck N 
  • Global histone H3K27 methylation levels are different in localized and metastatic prostate cancer. 
    Cancer Invest. 2012;30(2): 92-7 
    Ellinger J, Kahl P, von der Gathen J, Heukamp LC, Gütgemann I, Walter B, Hofstädter F, Bastian PJ, von Ruecker A, Müller SC, Rogenhofer S 
  • Development of hepatocellular carcinoma associated with anabolic androgenic steroid abuse in a young bodybuilder: a case report. 
    Case Report Pathol. 2012;2012: 195607 Hardt A, Stippel D, Odenthal M, Hölscher AH,Dienes HP, Drebber U 
  • NLRP10 enhances Shigella-induced pro-inflammatory responses. 
    Cell Microbiol. 2012;14(10): 1568-83 Lautz K, Damm A, Menning M, Wenger J, Adam AC, Zigrino P, Kremmer E, Kufer TA
  • TNF-induced target cell killing by CTL activated through cross-presentation. 
    Cell Rep. 2012;2(3): 478-87 Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Nieswandt B, van Rooijen N, Limmer A, Cederbrant K, Heikenwalder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA 
  • Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants. 
    Clin Cancer Res. 2012;18(17): 4682-90 Heuckmann JM, Balke-Want H, Malchers F, Peifer M, Sos ML, Koker M, Meder L, Lovly CM, Heukamp LC, Pao W, Küppers R, Thomas RK 
  • 68Ga-DOTATATE-PET/CT positive metastatic lymph node in a 69-year-old woman with Merkel cell carcinoma. 
    Clin Nucl Med. 2012;37(11): 1108-11 Schneider C, Schlaak M, Bludau M, Markiefka B, Schmidt MC 
  • Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. 
    Dev Dyn. 2012;241(4): 814-29 
    Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA 
  • The indications for liver biopsy. 
    Dtsch Arztebl Int. 2012;109(27-28): 477-83 Tannapfel A, Dienes HP, Lohse AW 
  • [De novo sarcoidosis after kidney transplantation]. 
    Dtsch Med Wochenschr. 2012;137(10): 476-8 Kisner T, Pfister R, Engels M, Benzing T, Michels G 
  • [48-year-old patient with progressive dyspnoea and recurrent syncope]. 
    Dtsch Med Wochenschr. 2012;137(41): 2097-100 Michels G, Drebber U, Pfister R 
  • [Early asymptomatic GIST of the stomach]. 
    Dtsch Med Wochenschr. 2012;137(33): 1650-3 Scherübl H, Faiss S, Jahn HU, Knoefel WT, Liehr RM, Schwertner C, Steinberg J, Stölzel U, Weinke T, Zimmer T, Wardelmann E 
  • AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis 
    EMBO J. 2012;31(20): 3961-3975 
    Hoepker Katja, Hagmann Henning, Khurshid Safiya, Chen Shuhua, Hasskamp Pia, Seeger-Nukpezah Tamina, Schilberg Katharina, Heukamp Lukas, Lamkemeyer Tobias, Sos MartinL, Thomas RomanK, Lowery Drew, Roels Frederik, Fischer Matthias, Liebau MaxC, Resch Ulrike, Kisner Tuelay, Roether Fabian, Bartram MalteP, Mueller RomanUlric, Fabretti Francesca, Kurschat Peter, Schumacher Bjoern, Gaestel Matthias, Medema ReneH, Yaffe MichaelB, Schermer Bernhard, Reinhardt HChristian, Benzing Thomas 
  • A peculiar case of autoimmune pancreatitis and sclerosing cholangitis 
    Endoscopy. 2012;44 2: E226-E227 
    Curth HM, Drebber U, Stippel D, Bangard C, Tox U, Steffen HM 
  • Prognostic value of proliferating cell nuclear antigen in parotid gland cancer. 
    Eur Arch Otorhinolaryngol. 2012;269(4): 1225-32 Stenner M, Demgensky A, Molls C,Hardt A, Luers JC, Grosheva M, Huebbers CU, Klussmann JP 
  • ALK(F1174L) is a driving oncogene of neuroblastoma in transgenic mice 
    Eur J Pediatr. 2012;171(9): 1429-1430 Schulte JH, Heukamp L, De Preter K, Thor T, Speleman F, Schramm A, Eggert A 
  • Prognostic impact of nodal micrometastasis in early esophageal cancer. 
    Eur J Surg Oncol. 2012;38(4): 314-8 Prenzel KL, Hölscher AH, Drebber U, Agavonova M, Gutschow CA, Bollschweiler E 
  • Azole-resistant invasive aspergillosis in a patient with acute myeloid leukaemia in Germany 
    Euro Surveill. 2012;17(36): 9-11 
    Hamprecht A, Buchheidt D, Vehreschild JJ, Cornely OA, Spiess B, Plum G, Halbsguth TV, Kutsch N, Stippel D, Kahl P, Persigehl T, Steinbach A, Bos B, Hallek M, Vehreschild MJ 
  • Gastrointestinal stromal tumors: evolving role of the multidisciplinary team approach in management. 
    Expert Rev Anticancer Ther. 2012;12(8): 1053-68 Reichardt P, Morosi C,Wardelmann E, Gronchi A 
  • Circulating microRNAs: promising candidates serving as novel biomarkers of acute hepatitis. 
    Front Physiol. 2012;3: 476 
    Elfimova N, Schlattjan M, Sowa JP, Dienes HP, Canbay A, Odenthal M 
  • microRNA are Central Players in Anti- and Profibrotic Gene Regulation during Liver Fibrosis. 
    Front Physiol. 2012;3: 49 
    Noetel A, Kwiecinski M, Elfimova N, Huang J, Odenthal M 
  • MicroRNA profiling of primary high-grade soft tissue sarcomas. 
    Genes Chromosomes Cancer. 2012;51(11): 982-96 Renner M, Czwan E, Hartmann W, Penzel R, Brors B, Eils R, Wardelmann E, Büttner R, Lichter P, Schirmacher P, Mechtersheimer G 
  • A dual role of linker histone H1.4 Lys 34 acetylation in transcriptional activation. 
    Genes Dev. 2012;26(8): 797-802 
    Kamieniarz K, Izzo A, Dundr M, Tropberger P, Ozretic L, Kirfel J, Scheer E, Tropel P, Wisniewski JR, Tora L, Viville S, Buettner R, Schneider R 
  • [Pedunculated mass of the aryepiglottic fold]. 
    HNO. 2012;60(12): 1093-5 
    Mikolajczak S, Quante G, Lüers JC, Drebber U, Beutner D 
  • Multiple craniocervical chordomas presenting as a parapharyngeal mass. 
    Head Neck. 2012; 
    Anagiotos A, Preuss SF, Drebber U, Jumah MD 
  • miRNA serum pattern in HIV-sero-positive individuals is changed by HCV-co-infection and HAART 
    Hepatology. 2012;56 1: 817A-817A 
    Anadol E, Schwarze-Zander C, Elfimova N, Boesecke C, Wasmuth JC, Sauerbruch T, Rockstroh J, Odenthal M, Trebicka J 
  • Circulating miRNAs as marker for liver injury in HIV-positive individuals 
    Hepatology. 2012;56 1: 262A-263A 
    Anadol E, Schwarze-Zander C, Elfimova N, Boesecke C, Wasmuth JC, Sauerbruch T, Rockstroh J, Odenthal M, Trebicka J 
  • Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice. 
    Hepatology. 2012;56(5): 1924-33 Höchst B, Schildberg FA, Böttcher J, Metzger C,Huss S, Türler A, Overhaus M, Knoblich A, Schneider B, Pantelis D, Kurts C, Kalff JC, Knolle P, Diehl L 
  • Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors. 
    Hepatology. 2012;55(1): 287-97 Hösel M, Broxtermann M, Janicki H, Esser K, Arzberger S, Hartmann P, Gillen S, Kleeff J, Stabenow D, Odenthal M, Knolle P, Hallek M, Protzer U, Büning H 
  • Hepatitis E Virus detection in liver biopsies of patients with acute hepatitis of unknown etiology 
    Hepatology. 2012;56 1: 964A-965A 
    Odenthal M, Aberle SW, Drebber U, Holzmann H, Dienes HP 
  • Hepatic and serum levels of miRNA 122 decrease with the severity of chronic HCV induced fibrosis 
    Hepatology. 2012;56 1: 818A-818A 
    Trebicka J, Anadol E, Elfimova N, Strack I, Wedemeyer I, Drebber U, Rockstroh J, Steffen HM, Roggendorf M, Viazov S, Holzmann H, Sauerbruch T, Dienes HP, Odenthal M 
  • Leiomyosarcoma of the inferior vena cava extending into the right atrium. A rare differential diagnosis of a right atrial tumor with fatal outcome. 
    Herz. 2012;37(5): 573-8 Lotze U, Reponova J, Muth G, Oltmanns G, Reich HC, Etzrodt G, Kaiser WA, Mutschke O, Ortmann M, Stippel D, Wahlers T 
  • Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization. 
    Histopathology. 2012;61(1): 59-68 Huss S, Wardelmann E, Goltz D, Binot E, Hartmann W, Merkelbach-Bruse S, Büttner R, Schildhaus HU 
  • The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C. 
    Int J Cancer. 2012;130(6): 1470-5 Nischalke HD, Coenen M, Berger C, Aldenhoff K, Müller T, Berg T, Krämer B, Körner C, Odenthal M, Schulze F, Grünhage F, Nattermann J, Sauerbruch T, Spengler U 
  • Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. 
    Int J Cancer. 2012;131(11): 2704-9 
    Willmann D, Lim S, Wetzel S, Metzger E, Jandausch A, Wilk W, Jung M, Forne I, Imhof A, Janzer A, Kirfel J, Waldmann H, Schüle R, Buettner R 
  • (68)Ga-DotaTATE PET-CT followed by Peptide Receptor Radiotherapy in combination with capecitabine in two patients with Merkel Cell Carcinoma. 
    Int J Clin Exp Med. 2012;5(4): 363-6 
    Schmidt MC, Uhrhan K, Markiefka B, Hasselbring L, Schlaak M, Cremer B, Kunze S, Baum RP, Dietlein M 
  • Evaluation of histological regression grading systems in the neoadjuvant therapy of rectal cancer: do they have prognostic impact? 
    Int J Colorectal Dis. 2012;27(10): 1295-301 Vallböhmer D, Bollschweiler E, Brabender J, Wedemeyer I, Grimminger PP, Metzger R, Schröder W, Gutschow C, Hölscher AH, Drebber U 
  • Effects of vascular photodynamic therapy in a newly adapted experimental rat aortic aneurysm model. 
    Interact Cardiovasc Thorac Surg. 2012;15(1): 69-72 Heckenkamp J, Luebke T, Theis T, Schumacher L, Gawenda M, Thul R, Fries JW, Brunkwall J 
  • The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology, and the metabolome of fibroblasts. 
    J Biol Chem. 2012;287(37): 30984-92 
    Janzer A, Stamm K, Becker A, Zimmer A, Buettner R, Kirfel J 
  • Risks of less common cancers in proven mutation carriers with lynch syndrome. 
    J Clin Oncol. 2012;30(35): 4409-15 Engel C, Loeffler M, Steinke V, Rahner N, Holinski-Feder E, Dietmaier W, Schackert HK, Goergens H, von Knebel Doeberitz M, Goecke TO, Schmiegel W, Buettner R, Moeslein G, Letteboer TG, García EG, Hes FJ, Hoogerbrugge N, Menko FH, van Os TA, Sijmons RH, Wagner A, Kluijt I, Propping P, Vasen HF 
  • [18F]Fluorodeoxyglucose positron emission tomography/computed tomography-positive gastric adenocarcinoma in a 12-year-old girl with Peutz-Jeghers syndrome. 
    J Clin Oncol. 2012;30(14): e140-3 Schneider C, Simon T, Hero B, Uphoff US, Drebber U, Alakus H, Holinski-Feder E, Berthold F, Dietlein M, Schmidt MC
  • Usefulness of imprint and brushing cytology in diagnosis of lung diseases with flexible bronchoscopy 
    J Clin Pathol. 2012;65(7): 649-653 
    Michels G, Topalidis T, Buttner R, Engels M, Pfister R 
  • Recent Comments BRAF Mutation Testing in metastatic malignant Melanoma 
    J Dtsch Dermatol Ges. 2012;10(6): 443-446 
    Dietel M, Enk A, Lehmann A, Bauer JN, Garbe C, Kellner U, Kirchner T, Jung A, Kreipe H,Merkelbach-Bruse S, Buttner R, Ruschoff J, Schlake W, Schirmacher P, Stadler R 
  • Neoadjuvant Radiochemotherapy in Adenocarcinoma of the Esophagus: ERCC1 Gene Polymorphisms for Prediction of Response and Prognosis. 
    J Gastrointest Surg. 2012;16(1): 26-34 Metzger R, Warnecke-Eberz U, Alakus H, Kütting F, Brabender J, Vallböhmer D, Grimminger PP, Mönig SP, Drebber U, Hölscher AH, Bollschweiler E 
  • TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function. 
    J Invest Dermatol. 2012;132(2): 337-45 Fehrenschild D, Galli U, Breiden B, Bloch W,Schettina P, Brodesser S, Brodesser S, Michels C, Günschmann C, Sandhoff K, Niessen CM, Niemann C 
  • Hepatocarcinogenesis in non-cirrhotic liver is associated with a reduced number of clonal hepatocellular patches in non-tumorous liver parenchyma. 
    J Pathol. 2012;228(3): 333-40 Adam AC, Faudou V, Paschen SA, Adam OM, Kahl P,Drebber U, Fischer HP, Büttner R 
  • DEVELOPMENTS IN TARGETED THERAPY: FGFR1 INHIBITION IN LUNG CANCER 
    J Thorac Oncol. 2012;7 S(6): S23-S23 Wolf J, Nogova L, Heukamp LC, Bos M, Schuler M, Sequist L, Tian GG, Ringeisen F, Buettner R, Thomas R 
  • Classifying prostate cancer malignancy by quantitative histomorphometry. 
    J Urol. 2012;187(5): 1867-75 
    Loeffler M, Greulich L, Scheibe P, Kahl P, Shaikhibrahim Z, Braumann UD, Kuska JP, Wernert N 
  • Glycyrrhizin in patients who failed previous interferon alpha-based therapies: biochemical and histological effects after 52 weeks. 
    J Viral Hepat. 2012;19(8): 537-46 Manns MP, Wedemeyer H, Singer A, Khomutjanskaja N, Dienes HP, Roskams T, Goldin R, Hehnke U, Inoue H, European SNMC Study Group , Stauber R, Hubmann R, Meieron A, Bourgeois S, Holvoet J, Horsmans Y, Reynaert H, Robaeys G, Hejda V, Dostal V, Kapla J, Plisek S, Horak J, Sperl J, Spicak J, Stransky J, Taimr P, Aua M, Koldits A, Margus B, Koiva P, Kull K, Labotkin K, Remmel H, Salupere R, Messmann H, Meyer U, Huber R, Buggisch P, Holm S, Manns M, Kallinowski B, Schiefke I, Böcher W, Niederau C, Marquardt T, Fuchs M, Abonyi M, Csak T, Folhoffer A, Horvath A, Lengyel G, Schuller J, Szabo O, Szalay F, Telegdy L, Tulassay Z, Werling K, Kuse V, Rozentale B, Sondore V, Viksna L, Kondrackiene J, Petrenkiene V, Ambrozaitis A, Balciuniene L, Denapiene G, Irnius A, Speiciene D, Titova B, Voinic A, Halota W, Paw?owska M, Topczewska-Staubach E, Cianciara J, Jab?o?ska J, Koz?owska J, Miku?a T, Czarnecki M, G?adysz A, Piszko P, Rotter K, Szymczak A, Morenets TM, Baikova I, Bakulin I, Blokhina N, Bogomolov P, Ignatova T, Maevskaya M, Mazurchik N, Nikitin I, Plusnin S, Sapronov G, Volochkova E, Voronkova N, Zharov S, Shmakova M, Morozov V, Zakharova N, Zhdanov K, Geyvandova N, Sitnikov I, Gubergrits N, Zagorenko Y, Zaytsev I, Shargorod I, Zvyagintseva T, Chaykovskaya T, Egorova T, Kharchenko N, Korulya I, Topolnitsky V, Khomutjanskaja N, Moroz L
  • Expression of platelet-derived growth factor-C and insulin-like growth factor I in hepatic stellate cells is inhibited by miR-29. 
    Lab Invest. 2012;92(7): 978-87 Kwiecinski M, Elfimova N, Noetel A, Töx U, Steffen HM, Hacker U, Nischt R, Dienes HP, Odenthal M 
  • Analysis of HPV Integration Sites in Oropharyngeal Squamous Cell Carcinomas 
    Lab Invest. 2012;92 1: 316A-316A 
    Speel EJM, Huebbers CU, Olthof NC, Kolligs J, Preuss SF, Drebber U, Kremer B, Klussmann JP 
  • Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial 
    Lancet Oncol. 2012;13(7): 679-687 
    Rodel C, Liersch T, Becker H, Fietkau R, Hohenberger W, Hothorn T, Graeven U, Arnold D, Lang-Welzenbach M, Raab HR, Sulberg H, Wittekind C, Potapov S, Staib L, Hess C, Weigang-Kohler K, Grabenbauer GG, Hoffmanns H, Lindemann F, Schlenska-Lange A, Folprecht G, Sauer R, German Rectal Canc Study Grp 
  • Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation. 
    Leukemia. 2012;26(9): 2039-51 
    Sprüssel A, Schulte JH, Weber S, Necke M, Händschke K, Thor T, Pajtler KW, Schramm A,König K, Diehl L, Mestdagh P, Vandesompele J, Speleman F, Jastrow H, Heukamp LC, Schüle R, Dührsen U, Buettner R, Eggert A, Göthert JR 
  • MicroRNAs: Small but amazing, and their association with endothelin. 
    Life Sci. 2012;91(13-14): 475-89 von Brandenstein M, Richter C, Fries JW 
  • ETS-dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells. 
    Life Sci. 2012;91(13-14): 562-71 
    von Brandenstein M, Schlosser M, Richter C, Depping R, Fries JW 
  • Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis. 
    Liver Int. 2012;32(9): 1342-53 
    Borkham-Kamphorst E, Huss S, Van de Leur E, Haas U, Weiskirchen R 
  • Definition of a fluorescence in situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer 
    Lung Cancer. 2012;77 1: S14-S14 
    Schmitz K, Schildhaus HU, Heukamp LC, Merkelbach-Bruse S, Wolf J, Buettner R 
  • Bronchogenic cyst mimicking ischemic heart disease. 
    Lung India. 2012;29(4): 376-7 
    Michels G, Bovenschulte H, Drebber U, Pfister R
  • Postradiation cutaneous angiosarcoma after treatment of breast carcinoma is characterized by MYC amplification in contrast to atypical vascular lesions after radiotherapy and control cases: clinicopathological, immunohistochemical and molecular analysis o 
    Mod Pathol. 2012;25(1): 75-85 
    Mentzel T, Schildhaus HU, Palmedo G, Büttner R, Kutzner H 
  • Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer. 
    Mod Pathol. 2012;25(11): 1473-80 Schildhaus HU, Heukamp LC, Merkelbach-Bruse S, Riesner K, Schmitz K, Binot E, Paggen E, Albus K, Schulte W, Ko YD, Schlesinger A, Ansén S, Engel-Riedel W, Brockmann M, Serke M, Gerigk U, Huss S, Göke F, Perner S, Hekmat K, Frank KF, Reiser M, Schnell R, Bos M, Mattonet C, Sos M, Stoelben E, Wolf J, Zander T,Buettner R 
  • Bats host major mammalian paramyxoviruses. 
    Nat Commun. 2012;3: 796 
    Drexler JF, Corman VM, Müller MA, Maganga GD, Vallo P, Binger T, Gloza-Rausch F, Rasche A, Yordanov S, Seebens A, Oppong S, Adu Sarkodie Y, Pongombo C, Lukashev AN, Schmidt-Chanasit J, Stöcker A, Carneiro AJ, Erbar S, Maisner A, Fronhoffs F, Buettner R, Kalko EK, Kruppa T, Franke CR, Kallies R, Yandoko ER, Herrler G, Reusken C, Hassanin A, Krüger DH, Matthee S, Ulrich RG, Leroy EM, Drosten C
  • LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. 
    Nat Genet. 2012;44(11): 1199-206 
    Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I,Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH 
  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. 
    Nat Genet. 2012;44(10): 1104-10 Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Carter SL, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DA, Snijders PJ, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Wolf J, Nürnberg P, Perner S, Heukamp LC, Heukamp LC, Brindle PK, Haas S, Thomas RK 
  • The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell lines 
    Naunyn Schmiedebergs Arch Pharmacol. 2012;385 1: 7-7 Bachmann HS, Akdeli N,Heukamp L, Schulte J, Siffert W 
  • RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. 
    Neoplasia. 2012;14(6): 526-34 von dem Knesebeck A, Felsberg J, Waha A, Hartmann W, Scheffler B, Glas M, Hammes J, Mikeska T, Yan PS, Endl E, Simon M, Reifenberger G, Pietsch T, Waha A
  • Liver cell transplantation in severe infantile oxalosis--a potential bridging procedure to orthotopic liver transplantation? 
    Nephrol Dial Transplant. 2012;27(7): 2984-9 
    Beck BB, Habbig S, Dittrich K, Stippel D, Kaul I, Koerber F, Goebel H, Salido EC, Kemper M, Meyburg J, Hoppe B 
  • Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas. 
    Neuro-oncol. 2012;14(7): 859-69 
    Künkele A, De Preter K, Heukamp L, Thor T, Pajtler KW, Hartmann W, Mittelbronn M, Grotzer MA, Deubzer HE, Speleman F, Schramm A, Eggert A, Schulte JH 
  • LYSIN-SPECIFIC HISTONE DEMETHYLASE 1 (LSD1) IS A PROMISING NEW EPIGENETIC THERAPY TARGET CRUCIALLY INVOLVED IN THE MIGRATION OF MEDULLOBLASTOMA CELLS
    Neuro-oncol. 2012;14 1: 92-92 
    Pajtler KW, Weingarten C, Thor T, Kuenkele A, Fleischhack G, Heukamp LC, Buettner R, Kirfel J, Eggert A, Schramm A, Schulte JH
  • miR-34a IS DISPENSABLE FOR NORMAL DEVELOPMENT BUT ITS LOSS ACCELERATES MEDULLOBLASTOMA FORMATION 
    Neuro-oncol. 2012;14 1: 89-89 
    Thor T, Mestdagh P, Vandesomple J, Fuchs H, Durner VG, de Angelis MH, Heukamp L, Kunkele A, Pajtler K, Eggert A, Schramm A, Schulte JH 
  • The prognostic impact of extracapsular lymph node involvement in rectal cancer patients: Implications for staging and adjuvant treatment strategies. 
    Oncol Lett. 2012;3(4): 825-830 
    Brabender J, Bollschweiler E, Hölscher AH, Strobel K, Gutschow C, Prenzel K, Grimminger P, Drebber U, Schröder W, Metzger R, Vallböhmer D
  • Evaluation of the clinical characteristics and natural history of patients with FGFR1 amplified squamous cell lung carcinoma 
    Onkologie. 2012;35 6: 137-138 
    Bos MCA, Gardizi M, Scheffler M, Heukamp L, Nogova L, Albus K, Koenig K, Schildhaus HU,Schmitz K, Merkelbach-Bruse S, Fassunke J, Binot E, Mattonet C, Kunstlinger H, Kleine M, Gokkurt E, Schlesinger A, Kappes R, Geist T, Kambartel K, Schnell R, Schulz H, Reiser M, Katay I, Behringer D, Gerigk U, Schulte W, Galetke W, Diet F, Randerath W, Brettner S, Engel-Riedel W, Brockmann M, Stoelben E, Ko YD, Buchenroth M, Benz J, Severin K, Mainka D, Schmitz S, Steinmetz T, Dietze L, Serke M, Bernards P, Schulte P, Laskowski U, Stier S, Sieber M, Heintges T, Hunerliturkoglu AN, Frank K, Hekmat K, Heldwein M, Thomas R, Buttner R, Wolf J, Zander T, Netzwerk Genomische Med 
  • Frequency and clinical characterization of NSCLC patients harbouring PIK3CA mutations screened in the Network Genomic Medicine Lung Cancer 
    Onkologie. 2012;35 6: 37-37 
    Gardizi M, Scheffier M, Bos M, Heukamp L, Nogova L, Schildhaus HU, Schmitz K,Merkelbach-Bruse S, Fassunke J, Binot E, Albus K, Kunstlinger H, Kleine M, Mattonet C, Gokkurt E, Schlesinger A, Kappes R, Geist T, Kambartel K, Schnell R, Schulz H, Behringer D, Gerigk U, Schulte W, Galetke W, Diet F, Randerath W, Kaminsky B, Brettner S, Engel-Riedel W, Brockmann M, Stoelben E, Ko YD, Buchenroth M, Benz J, Severin K, Schmitz S, Steinmetz T, Mainka D, Dietze L, Serke M, Bernards P, Schulte P, Laskowski U, Reiser MCA, Katay I, Stier S, Sieber M, Heintges T, Hunerliturkoglu A, Frank KCA, Topelt K, Hekmat K, Heldwein M, Thomas R, Buttner R, Wolf J, Wolf J, Zander T, Netzwerk Genomische Med Lungenkrebs 
  • Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation 
    Onkologie. 2012;35 6: 18-18 
    Gothert JR, Weber S, Sprussel A, Handschke K, Necke M, Jastrow H, Schule R, Duhrsen U,Buttner R, Eggert A, Schulte JH 
  • Early clinical evaluation of FGFR1 inhibition in lung cancer: Preliminary results of a phase I study in FGFR1 amplified lung cancer patients treated with BGJ398, a pan FGFR inhibitor 
    Onkologie. 2012;35 6: 137-137 
    Nogova L, Gardizi M, Bos MCA, Bitter E, Schildhaus HU, Heukamp LC, Topelt K, Zander T, Scheffler M, Mattonet C, Gokkurt E, Risse F, Schuler M, Sequist L, Tian GG, Ringeisen F, Thomas R, Buttner R, Wolf J, Wolf J 
  • The Role of Molecular Diagnostics in Cancer Diagnosis and Treatment 
    Onkologie. 2012;35 1: 8-12 
    Ozretic L, Heukamp LC, Odenthal M, Buettner R
  • MIMEB: A phase II trial to evaluate FDG-PET/FLT-PET and DCE-MRI for early prediction of efficacy in patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab 
    Onkologie. 2012;35 6: 138-139 
    Scheffler M, Bos M, Sos ML, Nogova L, Mattonet C, Gardizi M, Papachristou I, Kahraman D, Kobe C, Boellaard R, Lammertsma AA, Ullrich RT, Persigehl T, Heukamp L, Buttner R, Elter T, Topelt K, Engel-Riedel W, Stoelben E, Neumaier B, Dietlein M, Zander T, Wolf J, Wolf J 
  • Targeted Therapy of Soft Tissue Sarcomas 
    Onkologie. 2012;35 1: 21-27 
    Wardelmann E, Chemnitz JM, Wendtner CM
  • mplementation of real-time genetic diagnostics and personalized treatment of non-small cell lung cancer (NSCLC) in a regional screening network 
    Onkologie. 2012;35 6: 138-138 
    Zander T, Heukamp L, Bos M, Gardizi M, Scheffler M, Albus K, Konig K, Schildhaus HU,Schmitz K, Merkelbach-Bruse S, Fassunke J, Kunstlinger H, Kleine M, Binot E, Nogova L, Mattonet C, Gokkurt E, Schlesinger A, Kappes R, Kambartel K, Schnell R, Schulz H, Reiser M, Behringer D, Gerigk U, Schulte W, Galetke W, Diet F, Randerath W, Brettner S, Engel-Riedel W, Brockmann M, Stoelben E, Ko YD, Buchenroth M, Benz J, Severin K, Schmitz S, Steinmetz T, Mainka D, Dietze L, Serke M, Bernards P, Schulte P, Laskowski U, Stier S, Sieber M, Heintges T, Frank K, Hekmat K, Heldwein M, Thomas R, Buttner R, Wolf J, Network Genomic Med Lung Canc 
  • Podoplanin expression in oral leukoplakia: prognostic value and clinicopathological implications. 
    Oral Dis. 2012;18(7): 692-9 
    Kreppel M, Kreppel B, Drebber U, Wedemayer I, Rothamel D, Zöller JE, Scheer M 
  • Preoperative vs. postoperative radiochemotherapy in patients with N2 squamous cell carcinoma of the oral cavity. 
    Oral Oncol. 2012;48(10): 1019-24 Kreppel M, Eich HT, Brüggenolte C, Dreiseidler T, Rothamel D, Drebber U, Kübler A, Zöller JE, Scheer M 
  • Induction of apoptosis and up-regulation of cellular proliferation in oral leukoplakia cell lines inside electric field 
    Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(5): 644-654 
    Korraah A, Odenthal M, Kopp M, Vigneswaran N, Sacks PG, Dienes HP, Stutzer H, Niedermeier W 
  • Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells. 
    PLoS ONE. 2012;7(7): e41179 Bill A, Schmitz A, König K, Heukamp LC, Hannam JS, Famulok M 
  • Micro-RNA profiling in human serum reveals compartment-specific roles of miR-571 and miR-652 in liver cirrhosis. 
    PLoS ONE. 2012;7(3): e32999 Roderburg C, Mollnow T, Bongaerts B, Elfimova N, Vargas Cardenas D, Berger K, Zimmermann H, Koch A, Vucur M, Luedde M, Hellerbrand C,Odenthal M, Trautwein C, Tacke F, Luedde T 
  • Human papillomavirus type 8 interferes with a novel C/EBP?-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration. 
    PLoS Pathog. 2012;8(7): e1002833 Sperling T, O?dak M, Walch-Rückheim B,Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S
  • [BRAF mutation detection in metastatic melanoma]. 
    Pathologe. 2012;33(4): 352-6 
    Dietel M, Enk A, Lehmann A, Bauer J, Garbe C, Kellner U, Kirchner T, Jung A, Kreipe H,Merkelbach-Bruse S, Büttner R, Rüschoff J, Schlake W, Schirmacher P, Penzel R, Stadler R 
  • [Indications and limitations of fresh frozen sections in the pulmonary apparatus]. 
    Pathologe. 2012;33(5): 402-6 Pütz K, Engels M, Vollbrecht C, Heukamp LC, Adam AC,Büttner R 
  • [Translational research and diagnosis in GIST]. 
    Pathologe. 2012;33 Suppl 2: 273-7 Wardelmann E 
  • ALK(F1174L) IS A DRIVING ONCOGENE OF NEUROBLASTOMA IN TRANSGENIC MICE 
    Pediatr Blood Cancer. 2012;59(6): 989-989 Schulte J, Heukamp L, Thor T, Kumps C, De Preter K, De Wilde B, Vandesompele J, Speleman F, Schramm A, Eggert A 
  • A framework for identification of actionable cancer genome dependencies in small cell lung cancer. 
    Proc Natl Acad Sci U S A. 2012;109(42): 17034-9 Sos ML, Dietlein F, Peifer M, Schöttle J, Balke-Want H, Müller C, Koker M, Richters A, Heynck S, Malchers F, Heuckmann JM, Seidel D, Eyers PA, Ullrich RT, Antonchick AP, Vintonyak VV, Schneider PM, Ninomiya T, Waldmann H, Büttner R, Rauh D, Heukamp LC, Thomas RK 
  • Targeted expression of mutated ALK induces neuroblastoma in transgenic mice. 
    Sci Transl Med. 2012;4(141): 141ra91 
    Heukamp LC, Thor T, Schramm A, De Preter K, Kumps C, De Wilde B, Odersky A, Peifer M, Lindner S, Spruessel A, Pattyn F, Mestdagh P, Menten B, Kuhfittig-Kulle S, Künkele A,König K, Meder L, Chatterjee S, Ullrich RT, Schulte S, Vandesompele J, Speleman F,Büttner R, Eggert A, Schulte JH 
  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer (vol 2, 62ra93, 2010) 
    Sci Transl Med. 2012;4(130): 
    Weiss J, Sos ML, Seidel D, Peifer M, Zander T, Heuckmann JM, Ullrich RT, Menon R, Maier S, Soltermann A, Moch H, Wagener P, Fischer F, Heynck S, Koker M, Schottle J, Leenders F, Gabler F, Dabow I, Querings S, Heukamp LC, Balke-Want H, Ansen S, Rauh D, Baessmann I, Altmuller J, Wainer Z, Conron M, Wright G, Russell P, Solomon B, Brambilla E, Brambilla C, Lorimier P, Sollberg S, Brustugun OT, Engel-Riedel W, Ludwig C, Petersen I, Sanger J, Clement J, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman D, Cappuzzo F, Ligorio C, Damiani S, Hallek M, Beroukhim R, Pao W, Klebl B, Baumann M,Buettner R, Ernestus K, Stoelben E, Wolf J, Nurnberg P, Perner S, Thomas RK 
  • Pegylated interferon-based treatment in patients with advanced liver disease due to chronic delta hepatitis. 
    Turk J Gastroenterol. 2012;23(5): 560-8 
    Kabaçam G, Dalekos GN, Çakalo?lu Y, Zachou K, Bock T, Erhardt A, Zeuzem S, Tabak F, Yalçin K, Bozdayi AM, Dienes HP, Bozkaya H, Manns M, Wedemeyer H, Yurdaydin C Keratin 8 variants are associated with cryptogenic hepatitis. Virchows Arch. 2012;460(4): 389-97 Zierden M, Penner AH, Montesinos-Rongen M, Weferling M,Drebber U, Stift J, Fries JW, Odenthal M, Rosenkranz S, Dienes HP